ALL libraries (COBIB.SI union bibliographic/catalogue database)
-
Imunofenotipizacija limfocita periferne krvi u sindromu mononukleozeŽidovec, Snježana ...Objective: The aim of our research is the analysis of cellular immunity in clinically difficult cases of adult patients at the acute phase of infectious mononucleosis (IM) caused by Epstein-Barr ... virus. The main feature of the acutephase of IM is a self limiting lymphoproliferation involving both T- and B- lymphocytes accompanied by clinical symptoms such as fever, lymphadenopathyand hepatosplenomegaly. Method: We have analysed the expressionof several identification, activation and maturation cellular markers on peripheral blood lymphocytes in 5 patients with IM by flow cytometry. Results: We have determined the percentages and absolute counts of T- and B-lymphocytes, NK cells, CD4+ and CD8+ T-lymphocytes, non-MHC-restricted T-lymphocytes, activated T-lymphocytes (HLA-DR and CD38), naVve and memory CD4+ T-lymphocytes in the peripheral blood of IM patients and, matching healthy controls. The immunophenotyping profile in acute IM was identical in all patients: the percentages of T-lymphocytes and NK cells within normal ranges, decreased percentages of B-lymphocytes, significantly decreased percentages and markedly increased absolute counts of CD4+ T- lymphocytes, significant expansion of CD8+ T-lymphocytes, inverted CD4/CD8 ratios, increased expression of activation markers HLA-DR on CD3' T-lymphocytes and CD38 on CD8+ T-lymphocytes and perturbed ratio of naive and memory CD4+ T-lymphocytes in IM patients compared to healthy controls. Discussion: The results of flow cytometric analysis of peripheral blood lymphocytes in IM will be compared with standard cytological examination. The similarities between the immunophenotyping profiles of patients with acute IM and HIV-1 infection and the possible diagnostic application of flow cytometry in IM will also be discussed.Source: Okužbe s humanimi herpesvirusi : zbornik predavanj in praktikum (Str. 63-69)Type of material - conference contributionPublish date - 1999Language - croatianCOBISS.SI-ID - 10156249
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Shelf entry
Permalink
- URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year | Impact factor | Edition | Category | Classification | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Select the library membership card:
If the library membership card is not in the list,
add a new one.
DRS, in which the journal is indexed
Database name | Field | Year |
---|
Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
---|
Source: Personal bibliographies
and: SICRIS
Select pickup location:
Material pickup by post
Delivery address:
Address is missing from the member's data.
The address retrieval service is currently unavailable, please try again.
By clicking the "OK" button, you will confirm the pickup location selected above and complete the reservation process.
By clicking the "OK" button, you will confirm the above pickup location and delivery address, and complete the reservation process.
By clicking the "OK" button, you will confirm the address selected above and complete the reservation process.
Notification
Automatic login and reservation service currently not available. You can reserve the material on the Biblos portal or try again here later.
Subject headings in COBISS General List of Subject Headings
Select pickup location
The material from the parent unit is free. If the material is delivered to the pickup location from another unit, the library may charge you for this service.
Pickup location | Material status | Reservation |
---|
Reservation in progress
Please wait a moment.
Reservation was successful.
Reservation failed.
Reservation...
Membership card:
Pickup location: