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  • Visual fields in giant cell arteritis (Horton's disease) [Elektronski vir]
    Fakin, Ana ; Kerin, Viktorija ; Hawlina, Marko
    Background The purpose of this study was to investigate visual field defects in different clinical presentations of giant cell arteritis. Methodology Retrospective study of 36 patients from 1996-2010 ... with giant cell arteritis (67% female, average age 79, range 62-92 years), with typical clinical picture and/or positive biopsy (78%, 18/23 performed). Visual fields charted by Goldmann perimeter were categorized into specific categories. Respect for horizontal meridian was noted. Results Loss of vision was unilateral (65%) or bilateral (35%). The most common ischaemic lesions were anterior ischaemic optic neuropathy (AION; 16 unilateral, 4 bilateral) and posterior ischaemic optic neuropathy (PION; 5 unilateral, 5 bilateral). Other lesions included central retinal artery occlusion (CRAO) and internuclear ophthalmoplegia (INO). More than half of the affected eyes (53%) had visual acuity of counting fingers to no light perception. We observed 11 types of visual field defects. AION presented most commonly with peripheral island (35%) and sector defect (35%). Inferior altitudinal defect occurred in 18%. There was a tendency to affect nasal and inferior halves of visual fields. PION occurred in 31% of patients and most often presented with scotoma with orwithout peripheral defect. Conclusions AION most commonly presented with peripheral island (35%) or sector defect (35%). Visual field defects in AION almost universally showed respect for horizontal meridian, except where only small residual island remained. Inferior altitudinal defect occurred less commonly than expected (18%). PION was more prevalent in our study (31%) compared to others and most often presented with scotoma with or without peripheral defect.
    Source: Translational Neuroscience [Elektrionski vir]. - ISSN 2081-6936 (Vol. 2, no. 4, 2011, str. 325-330)
    Type of material - e-article ; adult, serious
    Publish date - 2011
    Language - english
    COBISS.SI-ID - 109484