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  • Hiperkalcemija pri kronični limfocitni levkemiji = Hypercalcaemia in chronic lymphocytic leukemia
    Glaser, Marjana
    Background. Hypercalcaemia is common in some lymphoproliferative diseases like myeloma and T cell chronic lymphocytic leukemia (T KLL). In patients with B cell chronic lymphocytic leukemia (B KLL) ... hypercalcaemia is described in only few patients. Our patients. We represent two patients with B KLL and hypercalcaemia. Conclusions. Hypercalcaemia is a rare complication of B KLL. Pathophysiologically it is attributed to the reaction between leukemia cells and osteoblasts. Malignant cells secrete local cytokines which stimulate osteoclasts. As a result, bone resorptions and hypercalcaemia appear. Rehidration and bisphosphonates normalise the calcium level, but have no influence on progress of the disease.
    Source: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 68, št. 11, 1999, str. 633-634)
    Type of material - article, component part ; adult, serious
    Publish date - 1999
    Language - slovenian
    COBISS.SI-ID - 10991833

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