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13.
Influenza vaccination of human immunodeficiency virus 1-infected patients receiving antiretroviral therapy
Banič, Stanko ...
In 13 human immunodeficiency virus 1 (HIV-1) infected patients receiving a highly active antiretroviral therapy (HAART) annual influenza vaccination was conducted. It was hoped that HAART would ...prevent a post-vaccination increase in HIV-1 load and potential adverse effects. Only two patients had an increased viral load on day 14 post vaccination (p.v.) At 6 months p.v., the majority of the patients had a significantly increased CD4 cell count and a significantly decreased viral load. This indicates that HAART can protect patients from adverse consequences of influenza vaccination. The production ofantibodies to the influenza A and B viruses in the HIV-infected patients wassubstantially lower than in healthy persons. We propose that HIV-positive patients receiving HAART should be subjected to annual influenza vaccination.
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