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  • Influence of Vagus Nerve Stimulation On Blood Pressure And Heart Rate In Patients With Epilepsy [Elektronski vir]
    Kopač, Matjaž, 1974- ; Rener-Primec, Zvonka
    Aim: to study the influence of parasympathetic stimulation with vagus nerve stimulation (VNS) device on blood pressure (BP) and heart rate (HR) in patients with pharmacoresistant epilepsy. Methods: ... 24-hour ambulatory blood pressure monitoring was done in two patients before and after the VNS device's surgical implantation. Results: Mean BP in older patients was 106.1/66.8 mmHg before and 105.0/64.5 mmHg post VNS device implantation. Mean BP in younger patients was 97.1/58.1 mmHg before and 101.0/60.8 mmHg post-implantation. The difference in mean BP was statistically non-significant in both patients. Mean HR in the older patients was 77 beats per minute (bpm) before and 71 bpm post-VNS device implantation, a statistically significant difference (p=0.009). Mean HR in the younger patients was 84 bpm before and 83 bpm post-implantation, a statistically non-significant difference. Conclusions: The vagus nerve stimulation did not result in a significant change of BP in both patients. However, it causes a substantial reduction in HR in one of them.
    Type of material - e-article ; adult, serious
    Publish date - 2023
    Language - english
    COBISS.SI-ID - 165319683