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Hemoragijska vrućica s bubrežnim sindromom: importirana i/ili autohtona bolestu Zadarskoj regiji = Hemorrhagic fever with renal syndrome: imported or native disease in the ZadarareaDželalija, Boris ; Medić, Alan ; Avšič-Županc, TatjanaAim: The aim of the study is to warn of the need of clinical hemorrhagic feverwith renal syndrome (HFRS) recognition and determination, and of the riskof its spread from a new focus of this natural ... zoonosis near Zadar (north Dalmatia), i. e., in the northern part (Lika) of the Zadar County. Method: Clinical and epidemiologic characteristics of HFRS were analyzed in four patients. Patient sera were analyzed for Puumala (PUU) and Hantaan (HTN) viruses by immunofluorescence test (IFT) and immunoenzyme test (ELISA). Results: Epidemiologic studies confirmed the source of infection to be out of the area in three patients, whereas in one patient it was near Zadar area. Mild symptoms pointed to the disease. Pathologic findings showed pathologic leukocyte values (leukocytosis), two-to tour-fold alanine aminotransferase, aspartate aminotransferase and creatinine increase in serum, proteinuria and erythrocyturia. A significant PUU antibody titer was found by serum IF and ELISA. Conclusion: The occurrence of HFRS in the Zadar area was confirmed by clinical description and laboratory evidence. The newly identified focus was in the vicinity of this area could imply a risk for the disease epidemic in the Zadar area.Source: Acta medica Croatica : časopis Hrvatske akademije medicinskih znanosti = the journal of the Croatian Academy of Medical Sciences. - ISSN 1330-0164 (Letn. 57, št. 5, 2003, str. 437-440)Type of material - article, component partPublish date - 2003Language - croatianCOBISS.SI-ID - 17399769
Author
Dželalija, Boris |
Medić, Alan |
Avšič-Županc, Tatjana
Topics
Hemorrhagic Fever With Renal Syndrome |
Diagnosis |
Etiology |
Hantavirus |
Isolation And Purification |
Fluorescent Antibody Technique, Indirect |
Igg |
Igm |
Croatia |
Hantavirus |
Hemoragična mrzlica z ledvičnim sindromom |
Fluorescenčno protitelo, tehnika indirektna |
Hrvaška |
IgG |
IgM
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Database name | Field | Year |
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Dželalija, Boris | |
Medić, Alan | |
Avšič-Županc, Tatjana | 10331 |
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