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Povečanje permeabilnosti stene sečnega mehurja prašiča s hitosanom in vpliv kalcijevih ionov = Permeability enhancment of porcine urinary bladder wall by chitosan and the effect of calcium ions : diplomska naloga
Podobnik, Blanka
Namen diplomskega dela je bil ugotoviti, ali kalcijevi ioni vplivajo na poveèanje absorpcije z 0,005% (utžvol) hitosanom in ali je ta vpliv koncentracijsko odvisen. Preuèevali smo tudi vpliv èasa ...stika disperzije hitosana z dodanimi 0,05 M kalcijevimi ioni s tkivom na kolièino absorbirane modelne uèinkovine.V dveh serijah Ćin vitroĆ poskusov na izoliranem seènem mehurju prasièa smo ugotovili, da dodatek 0,0005 M in 0,005 M kalcijevih ionovk 0,005% (utžvol) disperziji hitosana nima signifikantnega vpliva na delovanje hitosana, medtem ko ob dodatku 0,05 M kalcijevih ionov hitosan ne poveèa veè znaèilno permeabilnosti stene seènega mehurja. Èas stika disperzijehitosana z dodanimi 0,05 M kalcijevimi ioni s tkivom vpliva na kolièino absorbiranega moksifloksacina. Pri daljsem èasu stika disperzije s tkivom preide v tkivo veè moksifloksacina.
Type of material - undergraduate thesis
; adult, serious
Publication and manufacture - Ljubljana : [Podobnik, B.], 2005
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