ALL libraries (COBIB.SI union bibliographic/catalogue database)
-
Electroacupuncture prevents astrocyte atrophy to alleviate depression [Elektronski vir]Lin, Si-Si ...Astrocyte atrophy is the main histopathological hallmark of major depressive disorder (MDD) in humans and in animal models of depression. Here we show that electroacupuncture prevents astrocyte ... atrophy in the prefrontal cortex and alleviates depressive-like behaviour in mice subjected to chronic unpredictable mild stress (CUMS). Treatment of mice with CUMS induced depressive-like phenotypes as confirmed by sucrose preference test, tail suspension test, and forced swimming test. These behavioural changes were paralleled with morphological atrophy of astrocytes in the prefrontal cortex, revealed by analysis of 3D reconstructions of confocal Z-stack images of mCherry expressing astrocytes. This morphological atrophy was accompanied by a decrease in the expression of cytoskeletal linker Ezrin, associated with formation of astrocytic leaflets, which form astroglial synaptic cradle. Electroacupuncture at the acupoint ST36, as well as treatment with anti-depressant fluoxetine, prevented depressive-like behaviours, astrocytic atrophy, and down-regulation of astrocytic ezrin. In conclusion, our data further strengthen the notion of a primary role of astrocytic atrophy in depression and reveal astrocytes as cellular target for electroacupuncture in treatment of depressive disorders.Source: Cell death & disease [Elektronski vir]. - ISSN 2041-4889 (Vol. 14, iss. 5, [article no.] 343, 2023, str. 1-10)Type of material - e-articlePublish date - 2023Language - englishCOBISS.SI-ID - 178414595
Author
Lin, Si-Si |
Zhou, Bin |
Chen, Bin-Jie |
Jiang, Ruo-Tian |
Li, Baoman |
Illes, Peter |
Semyanov, Alexey |
Tang, Yong, nevrolog |
Verkhratsky, Alexei
Topics
electroacupuncture |
astrocytes |
atrophy |
alleviate depression |
elektroakupunktura |
astrociti |
atrofija |
lajšanje depresije
Shelf entry
Permalink
- URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year | Impact factor | Edition | Category | Classification | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Select the library membership card:
If the library membership card is not in the list,
add a new one.
DRS, in which the journal is indexed
Database name | Field | Year |
---|
Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
---|---|
Lin, Si-Si | |
Zhou, Bin | |
Chen, Bin-Jie | |
Jiang, Ruo-Tian | |
Li, Baoman | |
Illes, Peter | |
Semyanov, Alexey | |
Tang, Yong, nevrolog | |
Verkhratsky, Alexei | 37641 |
Source: Personal bibliographies
and: SICRIS
Select pickup location:
Material pickup by post
Delivery address:
Address is missing from the member's data.
The address retrieval service is currently unavailable, please try again.
By clicking the "OK" button, you will confirm the pickup location selected above and complete the reservation process.
By clicking the "OK" button, you will confirm the above pickup location and delivery address, and complete the reservation process.
By clicking the "OK" button, you will confirm the address selected above and complete the reservation process.
Notification
Automatic login and reservation service currently not available. You can reserve the material on the Biblos portal or try again here later.
Subject headings in COBISS General List of Subject Headings
Select pickup location
The material from the parent unit is free. If the material is delivered to the pickup location from another unit, the library may charge you for this service.
Pickup location | Material status | Reservation |
---|
Reservation in progress
Please wait a moment.
Reservation was successful.
Reservation failed.
Reservation...
Membership card:
Pickup location: