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Osteoporoza pri moških – pomen hipogonadizma = Osteoporosis in men – the importance of hypogonadismGroti Antonič, Kristina ; Kocjan, Tomaž, 1966-Osteoporoza je sistemska bolezen kosti z znižano mineralno kostno gostoto in spremenjeno mikroarhitekturo kostnine, kar vodi do zlomov ob majhni poškodbi. Čeprav pogosteje prizadene ženske, imajo ... moški zaradi osteoporoze več zapletov in višjo umrljivost po zlomih. Pri moških diagnozo osteoporoze večkrat postavimo šele po zlomu. Pogosteje je sekundarna, med najpomembnejšimi sekundarnimi vzroki je hipogonadizem, ki je prav tako podcenjeno, premalo prepoznano ter pre-redko diagnosticirano in zdravljeno stanje. Zdravljenje osteoporoze pri moških je kompleksno, vključuje nefarmakološke in farmakološke ukrepe. Cilj zdravljenja je preprečevanje zlomov. Nadomestno zdravljenje s testosteronom poleg pozitiv-nih učinkov na skelet pri hipogonadnih moških izboljša tudi kakovost življenja. Neposrednih dokazov, da bi zdravljenje s testosteronom zmanjšalo tveganje za osteoporozne zlome, zaenkrat ni. Pred uvedbo testosterona skupaj z bolnikom skrb-no pretehtamo koristi in tveganja. Bisfosfonati, denosumab in teriparatid izboljšajo mineralno kostno gostoto in zmanjša-jo tveganje za zlome vretenc. Učinkoviti so tudi pri moških z osteoporozo in s hipogonadizmom.Source: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 92, št. 11/12, 2023, str. 456-467)Type of material - article, component part ; adult, seriousPublish date - 2023Language - slovenianCOBISS.SI-ID - 179164931
Author
Groti Antonič, Kristina |
Kocjan, Tomaž, 1966-
Topics
osteoporoza |
hipogonadizem |
testosteron |
osteoporosis |
hypogonadism |
testosterone
source: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 92, št. 11/12, 2023, str. 456-467)
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Groti Antonič, Kristina | 51833 |
Kocjan, Tomaž, 1966- | 15783 |
Source: Personal bibliographies
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