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Surgical treatment of breast cancer in patients aged 80 years or older - how much is enough? [Elektronski vir]Bešić, Nikola ...Abstract BACKGROUND: The population of elderly people is increasing and so is the population of breast cancer patients aged >=80 years. The aim of our retrospective study was to identify independent ... prognostic factors for the duration of breast cancer-specific survival of surgically treated patients aged >=80 years. The secondary aim was to determine the appropriate surgical treatment of breast cancer in patients aged >=80 years. METHODS: We reviewed the medical records of 154 patients aged >=80 years with early-stage breast cancer (mean age 83 years) who underwent surgery at the tertiary cancer center in the period from 2000 to 2008. Tumor stage was pT1/pT2 and pT3/pT4 in 75% and 25%, respectively. Surgical treatment comprised: quadrantectomy (in 27%), mastectomy (in 73%), axillary dissection (in 57%), and sentinel lymph node biopsy (in 18%), while 25% of patients had no axillary surgery. RESULTS: During a median follow-up of 5.3 years, 31% of patients died of breast cancer, while 28% of patients died of other causes. Half of our patients with poorly differentiated breast cancer or estrogen receptor-negative tumor died of breast cancer. Multivariate statistical analysis showed that the pathological T-stage, pathological N-stage and estrogen receptors were independent prognostic factors for the duration of breast cancer-specific survival of patients. CONCLUSION: Short breast cancer-specific survival indicates that, in patients aged >=80 years, breast cancer with metastases in axillary lymph nodes can be an aggressive disease.Source: BMC cancer [Elektronski vir]. - ISSN 1471-2407 (Vol. , no. , 2014, str. [1-7])Type of material - e-articlePublish date - 2014Language - englishCOBISS.SI-ID - 1871227
Author
Bešić, Nikola |
Bešič, Hana |
Perić, Barbara, 1976- |
Pilko, Gašper |
Petrič, Rok, 1972- |
Žmuc, Jan |
Dzodić, Radan |
Perhavec, Andraž
Topics
rak dojke |
starejši |
zdravljenje |
prognoza |
breast cancer |
elderly |
treatment |
prognosis
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DRS, in which the journal is indexed
Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Bešić, Nikola | 10330 |
Bešič, Hana | ![]() |
Perić, Barbara, 1976- | 24299 |
Pilko, Gašper | 26531 |
Petrič, Rok, 1972- | 33364 |
Žmuc, Jan | 39826 |
Dzodić, Radan | ![]() |
Perhavec, Andraž | 26530 |
Source: Personal bibliographies
and: SICRIS
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