-
cAMP directly facilitates Ca-induced exocytosis in bovine lactotrophsSikdar, S... K. ; Zorec, Robert, 1958- ; Mason, W... T.We have used the whole cell patch clamp technique on single prolactin-secreting bovine lactotrophs to measure plasma membrane capacitance (Cm), an index of membrane surface area, under voltage-clamp ... during cytosol dialysis with Ca and cAMP. cAMP increased the magnitude and rate of Ca-induced exocytosis (Cm increase) without affecting membrane conductance; however, cAMP had no detectable effect on Cm when intracellular Ca was low. We thus report new evidence that cAMP can facilitate Ca-induced secretion in a synergistic fashion, by acting directly on the secretory apparatus, independently of membrane conductance activation.Source: FEBS letters. - ISSN 0014-5793 (Let. 273, št. 1-2, 1990, str. 150-154)Type of material - article, component partPublish date - 1990Language - englishCOBISS.SI-ID - 1873881
Author
Sikdar, S... K. |
Zorec, Robert, 1958- |
Mason, W... T.
Topics
Calcium |
Pharmacology |
Cyclic amp |
Pharmacology |
Exocytosis |
Drug effects |
Pituitary gland, anterior |
Physiology |
Prolactin |
Secretion |
Calcium |
Metabolism |
Cattle |
Cell membrane |
Drug effects |
Physiology |
Cells, cultured |
Egtazic acid |
Pharmacology |
Electric conductivity |
Kinetics |
Membrane potentials |
Drug effects |
Pituitary gland, anterior |
Drug effects |
Secretion
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Shelf entry
Permalink
- URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year | Impact factor | Edition | Category | Classification | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Select the library membership card:
DRS, in which the journal is indexed
Database name | Field | Year |
---|
Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
---|---|
Zorec, Robert, 1958- | 03702 |
Select pickup location:
Material pickup by post
Notification
Subject headings in COBISS General List of Subject Headings
Select pickup location
Pickup location | Material status | Reservation |
---|
Please wait a moment.