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Small uterine septa (AFS class 6) represent an important risk variable for preterm birth and spontaneous abortion
Tomaževič, Tomaž ...
We compared pregnancy outcomes before and after hysteroscopic dissection of small and large uterine septa. The study involved 933 women after hysteroscopic dissection of a uterine septum: 483 women ...with a large septum (1.5 cm to total) and 450 women with a small septum (11.5 cm). The structure of 957 pregnancies before the operation differed significantly from the structure of 564 pregnancies after the operation (P<0.000). The spontaneous abortion rates decreased from 83% to 19% (P<0.00000) in the women with a largeseptum, and from 82% to 16% in the women with a small septum (P<0.0000). The preterm birth rates decreased from 43% to 9% in the large septum group (P<0.00001), and from 40% to 11% (P<0.0000) in the small septum group. The birth weight of neonates after surgery increased and the incidence of neonateswith birth weight less than 1500 g decreased. The referral of the neonates to the intensive care unit was signiticantly reduced (P<0.000). Therewas a signiticant reduction of fetal stillbirth and neonatal mortality rates (P<0.01). Besides large uterine septa, small uterine septa represent an important hysteroscopically preventable risk variable for preterm birth and spontaneous abortion.
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