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  • A simplified longitudinal model for the development of Type 2 Diabetes Mellitus
    De Gaetano, Andrea ...
    Obesity and diabetes are a progressively more and more deleterious hallmark of modern, well fed societies. In order to study the potential impact of strategies designed to obviate the pathological ... consequences of detrimental lifestyles, a model for the development of Type 2 diabetes geared towards large population simulations would be useful. The present work introduces such a model, representing in simplified fashion the interplay between average glycemia, average insulinemia and functional beta-cell mass, and incorporating the effects of excess food intake or, conversely, of physical activity levels. Qualitative properties of the model are formally established and simulations are shown as examples of its use.
    Source: Journal of theoretical biology. - ISSN 0022-5193 (Vol. 587, [article no.] 111822, June 2024, 17 str.)
    Type of material - article, component part ; adult, serious
    Publish date - 2024
    Language - english
    COBISS.SI-ID - 195458307
    DOI

source: Journal of theoretical biology. - ISSN 0022-5193 (Vol. 587, [article no.] 111822, June 2024, 17 str.)
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