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Perilous paradigm of graphene oxide and its derivatives in biomedical applicationsAyreen, Zobia ...With advancements in nanotechnology and innovative materials, Graphene Oxide nanoparticles (GONP) have attracted lots of attention among the diverse types of nanomaterials owing to their distinctive ... physicochemical characteristics. However, the usage at scientific and industrial level has also raised concern to their toxicological interaction with biological system. Understanding these interactions is crucial for developing guidelines and recommendations for applications of GONP in various sectors, like biomedicine and environmental technologies. This review offers crucial insights and an in-depth analysis to the biological processes associated with GONP immunotoxicity with multiple cell lines including human whole blood cultures, dendritic cells, macrophages, and multiple cancer cell lines. The complicated interactions between graphene oxide nanoparticles and the immune system, are highlighted in this work, which reveals a range of immunotoxic consequences like inflammation, immunosuppression, immunostimulation, hypersensitivity, autoimmunity, and cellular malfunction. Moreover, the immunotoxic effects are also highlighted with respect to in vivo models like mice and zebrafish, insighting GO Nanoparticles’ cytotoxicity. The study provides invaluable review for researchers, policymakers, and industrialist to understand and exploit the beneficial applications of GONP with a controlled measure to human health and the environmentSource: Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie. - ISSN 0753-3322 (Vol. 176, Art. 116842, 2024, 22 str.)Type of material - article, component partPublish date - 2024Language - englishCOBISS.SI-ID - 197848067
Author
Ayreen, Zobia |
Khatoon, Uzma |
Kirti, Apoorv |
Sinha, Adrija |
Gupta, Abha |
Yadav, Anu |
Mohanty, Rupali |
Chouhan, Raghuraj S.
Topics
kemija okolja |
nanodelci |
imunski sistem
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source: Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie. - ISSN 0753-3322 (Vol. 176, Art. 116842, 2024, 22 str.)
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Ayreen, Zobia | ![]() |
Khatoon, Uzma | ![]() |
Kirti, Apoorv | ![]() |
Sinha, Adrija | ![]() |
Gupta, Abha | ![]() |
Yadav, Anu | ![]() |
Mohanty, Rupali | ![]() |
Chouhan, Raghuraj S. | 50853 |
Source: Personal bibliographies
and: SICRIS
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