ALL libraries (COBIB.SI union bibliographic/catalogue database)
13.
Jedrne značilke seroznih tumorjev jajčnika : doktorsko delo
Strojan Fležar, Margareta
Image cytometric nuclear texture features (NTF) represent chromatin structure and organisationč therefore, they could be used as a surrogate end-point marker of the chromatin changes during ...neoplastic transformation of cells. Thepurpose of our study was to find out whether, a) a single NTF or a combination of NTF could discriminate between serous borderline malignant ovarian tumors and ovarian carcinomasč b) NTF could discriminate between borderline malignant tumors and different grades or stages of ovarian carcinomač c) different grades or stages in the carcinoma group could also be classified accordingly, using NTF. Finally, we analysed the discriminative power of NTF regarding the survival of the patients with ovarian carcinomas. In our study we analysed NTF of 43 serous borderline malignant tumors and 67 carcinomas of the ovary. Archival tissue samples of ovarian tumors were used for the preparation of single cell suspensions according to the modified Hedleyćs method. Cell monolayer slides were stained according to the Feulgen-thionine method. Image cytometric analysis was performed by using an authomated high resolution image cytometer, namely Cyto-SavantTM. The results of our study showed that a single NTF could discriminate between borderline malignant tumors and carcinomas, whereas an excellent discrimination was achieved using a combination of three NTF (93%). A single NTF could reliably discriminate between borderline malignant tumors and poorly differentiated carcinomas or carcinomas in FIGO stage III and IV, however, the discriminationwas less successful when discriminating borderline malignant tumors from well and moderately differentiated carcinomas or carcinomas in FIGO stage I and II. (Abstract truncated at 2000 characters.)
Type of material - dissertation
Publication and manufacture - Ljubljana : [M. Fležar], 2000
It was not necessary to add the material to the shelf.
Bibliographic material was successfully added on shelf.
Adding bibliographical material on shelf was not successful.
Material is already on the shelf.
Permalink
URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year
Impact factor
Edition
Category
Classification
JCR
SNIP
JCR
SNIP
JCR
SNIP
JCR
SNIP
Select the library membership card:
DRS,
in which the journal is indexed
Database name
Field
Year
Links to authors' personal bibliographies
Links to information on researchers in the SICRIS system
Subject headings in COBISS General List of Subject Headings
Select pickup location
The material from the parent unit is free. If the material is delivered to the pickup location from another unit, the library may charge you for this service.
