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Relevance of Tc-99m DMSA scintigraphy in renal transplant parenchymal imagingBudihna, Nataša, 1943- ...Tc-99m DMSA renal scintigraphy was performed in 40 renal grafts. Cyclosporin Aand glucocorticoids were given to all patients as antirejection therapy, and 11 also were given azathioprine. The kidneys ... were transplanted 1 to 97 months before the investigation. Seventy percent of kidneys had diffusely altered distribution of Tc-99m DMSA, and 43 percent had focal clear-cut parenchymal defects. The frequency of parenchymal defects observed on the DMSA scans was higher in patients who suffered manifest acute rejection episodes (8/16 versus9/24 patients, borderline significance, P less th. 0.06), but had no relation to the living or cadaveric donor transplant or its function. A combination of peritubular edema and interstitial fibrosis is considered the most probable explanation of diffuse changes. The high frequency of clear-cut parenchymal defects most likely results from symptomatic or asymptomatic rejection episodes complicated by renal transplant infarcts.Source: Clinical nuclear medicine. - ISSN 0363-9762 (Let. 19, št. 9, 1994, str. 782-784)Type of material - article, component partPublish date - 1994Language - englishCOBISS.SI-ID - 22745
Author
Budihna, Nataša, 1943- |
Milčinski, Metka |
Kajtna-Koselj, Mira |
Malovrh, Marko
Topics
Graft rejection |
Radionuclide imaging |
Kidney |
Radionuclide imaging |
Kidney transplantation |
Radionuclide imaging |
Organotechnetium compounds |
Diagnostic use |
Succimer |
Diagnostic use |
Acute disease |
Adult |
Azathioprine |
Therapeutic use |
Creatinine |
Blood |
Cyclosporine |
Therapeutic use |
Edema |
Metabolism |
Fibrosis |
Glucocorticoids |
Therapeutic use |
Graft rejection |
Metabolism |
Prevention and control |
Infarction |
Metabolism |
Kidney |
Blood supply |
Metabolism |
Kidney transplantation |
Pathology |
Kidney tubules |
Metabolism |
Middle age |
Organotechnetium compounds |
Pharmacokinetics |
Succimer |
Pharmacokinetics |
Adult |
Female |
Human |
Male |
Middle age
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Database name | Field | Year |
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Budihna, Nataša, 1943- | 04491 |
Milčinski, Metka | 09070 |
Kajtna-Koselj, Mira | 01979 |
Malovrh, Marko | 06203 |
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