Akademska digitalna zbirka SLovenije - logo
ALL libraries (COBIB.SI union bibliographic/catalogue database)
  • Relation of ultrasound morphologic characteristics of central pulmonary artery thromboemboli to their ex vivo lysibility
    Podbregar, Matej ...
    BACKGROUND: Ultrasound morphology of massive central pulmonary artery thromboemboli (TE) is an independent predictor of 30-day mortality. The aim ofthis study was to asses ex vivo lysibility of ... morphologically different TE. METHODS: Forty-five central pulmonary artery TE, collected at autopsies, were divided into hypoechoic (group A) and hyperechoic (group B) categories. TE were lysed with alteplase in a perfusing system simulating pulmonary circulation for 1 hour. RESULTS: The grey scale mean of thrombi in group B washigher compared with group A (64 +/- 7 vs. 38 +/- 7, respectively, P < .01). Spontaneous lysis in group A did not differ compared with group B (2.2% +/- 0.5% vs. 2.1% +/- 0.4%, P = .4). After incubation with alteplase, the weight of TE was reduced more in group A than in group B (16% +/- 2% vs. 11% +/- 2%, P < .001). The grey scale mean negatively correlated with the percentage of TE weight reduction (0.768) (P < .001). CONCLUSION: Ultrasound morphology of TE from central pulmonary arteries correlates significantly withex vivo lysibility. Hypoechoic TE are more susceptible to thrombolysis than hyperechoic TE.
    Source: Journal of the American Society of Echocardiography. - ISSN 0894-7317 (Letn. 20, št. 3, 2007, str. 276-280)
    Type of material - article, component part
    Publish date - 2007
    Language - english
    COBISS.SI-ID - 23066585

Shelf entry