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Histomorphological assessment of phlebitis in renal allograftsJurčić, Vesna ...Aim: To evaluate the histomorphological features of veins in normal and transplanted kidneys. Methods: Between 1992 and 1997, we semiquantitatively evaluated histomorphological changes in veins in ... nephrectomy specimens of 29 renal allografts with rejection and in 31 control kidneys. The structure of different segments of renal veins was additionally analyzed. Results: Small interlobular veins were composed of endothelium and basement membrane, similarto capillaries, while the walls of large interlobular and arcuate veinshad smooth muscle cell bundles forming the medial layer, similar to largeextrarenal veins. In the control group, only focal mononuclear infiltration around small interlobular veins was found (8/31). In rejected kidney allografts, the veins were frequently infiltrated with inflammatory cells, predominantly T lymphocytes and macrophages (29/29). Other changes included thrombosis (16/29), fibrinoid necrosis (7/29), and sclerosis (9/29), and in one case an intimal lipid deposition. Conclusion: This study, performedon whole explanted kidney specimens, revealed that rejection vasculitis often involved extrarenal and intrarenal veins, showing a whole spectrum of histopathological changes similar to those in arteries. Since large intrarenal veins have a muscle wall, we believe that the term "rejectionphlebitis" could be used in renal transplant pathology.Source: Croatian medical journal. - ISSN 0353-9504 (Letn. 48, št. 3, 2007, str. 327-332)Type of material - article, component partPublish date - 2007Language - englishCOBISS.SI-ID - 23664601
Author
Jurčić, Vesna |
Jeruc, Jera |
Marić, Stela |
Ferluga, Dušan, 1934-
Topics
Kidney Transplantation |
Child |
Graft Rejection |
Pathology |
Phlebitis |
Pathology |
Renal Veins |
Pathology |
Adult |
Ledvica, presaditev |
Flebitis |
Ledvične vene |
Odrasli |
Otrok |
Vsadek, zavrnitev
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Jurčić, Vesna | 11204 |
Jeruc, Jera | 19130 |
Marić, Stela | ![]() |
Ferluga, Dušan, 1934- | 02273 |
Source: Personal bibliographies
and: SICRIS
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