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Dinamika cerebralne oksigenacije pri hiperventilaciji in hipoventilaciji [Elektronski vir] = The dynamics of cerebral oxygenation during hyperventilation and hypoventilationRotman, Eva ; Križmarić, MiljenkoUvod: Možgani za svoje delovanje potrebujejo stalen dotok krvi, ki se med hiperventilacijo in hipoventilacijo spreminja. Namen študije je bil ugotoviti, ali lahko v teh dveh primerih zaznamo ... spremembe nasičenosti kisika v možganih (rSO2). Metode: Kvantitativno raziskavo smo izvedli na štirih zdravih prostovoljcih, pri katerih smo med kratkotrajno hiperventilacijo in hipoventilacijo spremljali rSO2 v možganih s spektroskopijo v bližnjem infrardečem polju (NIRS INVOS). Monitorirali smo tudi ostale fiziološke spremenljivke: dihanje, pulz, delni tlak ogljikovega dioksida (PETCO2) in nasičenost hemoglobina s kisikom v arterijski krvi (SpO2). Rezultati: Med hiperventilacijo ugotavljamo največji padec povprečne rSO2 za 3 % (s 57 % 1 % na 54 % 2 %), pri tem zasledimo padec delnega tlaka PETCO2 z 31 % 2 mmHg na 21 % 3 mmHg. Povprečna nasičenost hemoglobina s kisikom v periferni arterijski krvi je znašala 98 % in se je pri vseh preiskovancih dvignila za 1 do 2 %. Frekvenca srca se med hiperventilacijo poveča, med počitkom pa se ponovno zmanjša. Razlike v nasičenosti s kisikom med levo in desno možgansko hemisfero so bile od 2 % do maksimalnih 7 %. Razprava in zaključek: Zaradi mehanizma hipokapnije se ožilje v možganih skrči in zmanjša se dostava kisika. Pojav zmanjšanja rSO2 smo uspeli dokazati pri treh od štirih preiskovancih.Source: Zbornik prispevkov z recenzijo [Elektronski vir] = Proceedings book with review (Str. 804-809)Type of material - conference contributionPublish date - 2018Language - slovenianCOBISS.SI-ID - 2401188
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| Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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| Rotman, Eva |  |
| Križmarić, Miljenko | 25641 |
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