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Farmakogenomika in informacijski izzivi = Pharmacogenomics and informatical challengesFerk, Polonca ; Leskošek, BranimirPharmacogenomics is an interdisciplinary field which merges knowledge from pharmacology and genomics. Its basic aim is to find out how the unique genotype of an individual determines specific ... pharmacological responses. To beable to discover clinically relevant associations between the specific genotype and pharmacological response, huge amounts of data should be collected from different sources and further analyzed which is possible only by using suitable and effective informatics tools. In the paper a clinically relevant pharmacogenomic example is first presented and then contemporary informatics challenges are described.Source: Informatica medica slovenica. - ISSN 1318-2129 (Letn. 13, št. 1, 2008, str. 33-40)Type of material - article, component partPublish date - 2008Language - slovenianCOBISS.SI-ID - 24777945
Author
Ferk, Polonca |
Leskošek, Branimir
Topics
Pharmacogenetics |
Polymorphism (Genetics) |
Genotype |
Information Systems |
Cytochrome P-450 Cyp2d6 |
Alleles |
Breast Neoplasms |
Drug Therapy |
Tamoxifen |
Survival Analysis |
Farmakogenetika |
Polimorfizem (genetika) |
Genotip |
Informacijski sistemi |
Citokrom P-450 CYP2D6 |
Preživetje, analiza |
Dojka, novotvorbe |
Tamoksifen |
Aleli
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Database name | Field | Year |
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Ferk, Polonca | 22621 |
Leskošek, Branimir | 15355 |
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