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  • Herpes zoster following intra-articular corticosteroid injection
    Fernandes, Neil F. ...
    Localized herpes zoster following intra-articular corticosteroid injection is remarkable. We describe an 80-year-old woman with severe osteoarthritis that received an intra-articular injection of 80 ... mg methylprednisolone in her knee,followed 1 day later by the appearance of linear unilateral vesicles and bullae on her leg in a dermatomal distribution adjacent to the injection site.The roofs of several blisters showed classic viral cytopathic effects forherpes including keratinocytes with multinucleation and margination of chromatin. Varicella zoster virus immunostaining revealed positive staining inthe keratinocytes. One plausible explanation is herpes zoster virus reactivation secondary to localized immunosuppression from corticosteroid injection.
    Source: Acta dermatovenerologica Alpina, Panonica et Adriatica. - ISSN 1318-4458 (Vol. 18, no. 1, 2009, str. 28-30)
    Type of material - article, component part
    Publish date - 2009
    Language - english
    COBISS.SI-ID - 25731033

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    Digitalna knjižnica Slovenije - dLib.si

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