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Inflammatory biomarkers in heart failure revisited : much more than innocent bystandersVon Haehling, Stephan ...Chronic heart failure is viewed as a state of chronic inflammation. Many inflammatory markers have been shown to be up-regulated in patients who have this condition, but the markers' roles in ... clinical decision making have not yet been fully elucidated. A panel of biomarkers is likely to have a strong impact on patient management. Inflammatory biomarkers are interesting candidates that could answer specific clinical questions on their own or complement a multi-marker approach. This article provides a broad overview of several inflammatory biomarkers, including the pro-inflammatory cytokines tumor necrosis factor-alpha, interleukin (IL)-6, IL-1, IL-18, and the soluble receptors TNFR-1, TNFR-2, IL-6R, and gp130. In addition to these acute phase reactants, several adhesion molecules, and lipopolysaccharide-signaling pathways are discussed.Source: Heart failure clinics. - ISSN 1551-7136 (Letn. 5, št. 4, 2009, str. 549-560)Type of material - e-articlePublish date - 2009Language - englishCOBISS.SI-ID - 25781721
Author
Von Haehling, Stephan |
Schefold, Joerg C. |
Lainščak, Mitja |
Doehner, Wolfram |
Anker, Stefan D.
Topics
Heart Failure, Congestive |
Biological Markers |
Inflammation |
Cytokines |
Tumor Necrosis Factor |
C-Reactive Protein |
Acute-Phase Proteins |
P-Selectin |
Lipopolysaccharides |
Interleukin-6 |
Vnetje |
Tumor nekrotizirajoči faktor |
Citokini |
Srce, odpoved kongestivna |
Biološki označevalci |
Akutna-faza beljakovine |
Interlevkin-6 |
P-selektin |
Lipopolisaharidi |
C-reaktivna beljakovina
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Database name | Field | Year |
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Von Haehling, Stephan | |
Schefold, Joerg C. | |
Lainščak, Mitja | 22680 |
Doehner, Wolfram | |
Anker, Stefan D. |
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