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Metabolični sindrom: zgodovina, opredelitev in klinični pomen pri otrocih = Metabolic syndrome: history, definition and clinical significance in childrenGregorič, Alojz, 1940- ; Marčun-Varda, NatašaMetabolični sindrom je skupek dejavnikov tveganja metaboličnega izvora, ki jih spremlja povečano tveganje za razvoj aterosklerotičnih srčno-žilnih bolezni in sladkorne bolezni tipa 2. Ti dejavniki ... tveganja so aterogena dislipidemija, zvišan krvni tlak, zvišana glukoza v krvi, protrombotično in provnetno stanje. Glavna dejavnika tveganja za nastanek metaboličnega sindroma pa sta vsekakor debelost in neodzivnost na insulin. Metabolični sindrom dodatno poslabšujejo telesna nedejavnost, starost in endokrini ter genetski dejavniki. Sindrom ima svoj izvor v otroški dobi. Začenja se s slabo izraženimi dejavniki tveganja in nato napreduje. Pri mnogih bolnikih preide v sladkorno bolezen tipa 2, kar še povečuje tveganje za srčno-žilne bolezni. Članek podaja kratek pregled zgodovine, opredelitev in klinični pomen metaboličnega sindroma pri otrocih (prevalenca, etiologija, preventiva in zdravljenje). Nujno bi bilo, da se sprejme mednarodno priznana definicija metaboličnega sindroma pri otrocih. V zaključku predlagamo svojo definicijo. Metabolični sindrom ne sme postati samo nov sindrom v pediatriji, ampak mora glede na epidemično širjenje debelosti pri otrocih predstavljati izziv za boljšo preprečevanje srčno-žilnih bolezni. Upoštevajoč Luksemburško deklaracijo Slovenija uspešno pripravlja svojo integrirano strategijo preprečevanja srčno-žilnih bolezni.Source: Metabolični sindrom pri otrocih ; Sodobni način življenja in imunski odziv pri otrocih ; Racionalna uporaba zdravil v pediatriji : zbornik (Str. 17-24)Type of material - conference contribution ; adult, seriousPublish date - 2007Language - slovenianCOBISS.SI-ID - 2614847
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Gregorič, Alojz, 1940- | 03299 |
Marčun-Varda, Nataša | 15998 |
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