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Akutna ledvična okvara po operaciji na srcu = Acute kidney injury after heart surgery
Gavrić, Aleksandar, dr. med. ; Kališnik, Jurij-Matija
Akutna ledvična okvara (ALO) po operaciji na srcu pomembno vpliva na pooperativno okrevanje. Že blage okvare ledvične funkcije, pri katerih pride le do majhnega porasta kreatinina, poslabšajo ...kratkoročno in dolgoročno preživetje po operaciji. Mednarodne raziskave ugotavljajo, da je incidenca ALO po srčnih operacijah 2%40 %. Razlika v incidenci med raziskavami je predvsem posledica neenotnega diagnostičnega kriterija ALO in razlik v prei- skovalnih skupinah. V članku opišemo tri najpogostejše diagnostične kriterije ALO. Problem v diagnostiki predstavlja tudi določanje ALO na podlagi sprememb v koncentraciji serumskega kreatinina, ki se pojavijo šele v 24 urah po začetku ledvične okvare. Z odkrivanjem novih bioloških označevalcev bi lahko hitreje postavili diagnozo in tako prej zdravili ter potencialno preprečili nadaljnjo ledvično okvaro.
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