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13.
Biološka zdravila in vnetne revmatične bolezni = Biologics and rheumatologic diseases
Holc, Iztok, 1963- ...
Uvod. Revmatoidni artritis je kronična progresivna vnetna bolezen multifaktorielne etiologije. Ključnega pomena pri etiopatogenezi so citokini; med njimi tudi TNF-[alfa] in interlevkini (IL-1 in ...IL-6). Le ti igrajo pomembno vlogo tudi pri razvoju spondiloartritisov. Pomembno vlogo v T celičnem odgovoru pri bolnikih z revmatoidnim artritisom imajo tudi visoko efektivne antigen predstavitvene B celice. Namen. Predstaviti zdravljenje revmatoidnega artritisa in spondiloartritisov z biološkimi zdravili. Zaključki. Razvoj bioloških zdravil je privedel do pomembnega napredka v zdravljenju revmatoidnega artritisa in spondiloartritisov. Vendar to zdravljenje spremljajo tudi možni stranski učinki, na katere je treba biti pozoren.
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