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Vpliv intenzivnega glikemičnega nadzora na srčno-žilne bolezni
Zavratnik, Andrej
Vpliv intenzivnega glikemičnega nadzora na pojavnost srčno-žilnih bolezni in umrljivost je bil pred objavo rezultatov raziskav post-UKPDS, EDIC, ADVANCE, ACCORD in VADT manj jasen. Raziskavi ...post-UKPDS in EDIC sta potrdili pomembno vlogo intenzivnega glikemičnega nadzora in obstoj glikemičnega spomina pri bolnikih s sladkorno boleznijo tipa 2 v primarni preventivi srčno-žilnih bolezni. Raziskave ADVANCE, ACCORD in VADT z bolniki s sladkorno boleznijo tipa 2 in velikim tveganjem za srčno-žilne bolezni pa koristi intenzivnega nadzora glikemije pri preprečevanju srčno-žilnih bolezni niso potrdile. V raziskavi ACCORD je bil le ta celo povezan z večjo umrljivostjo. K nadzoru glikemije je treba pristopati individualno, glede na bolnikove značilnosti, sočasno pa učinkovito zdraviti ostale dejavnike tveganja.
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