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Anaplasmosis in dogs : the relation of haematological, biochemical and clinical alterations to antibody titre and PCR confirmed infectionRavnik Verbič, Urška ...Laboratory and clinical parameters of 149 dogs, exposed to Anaplasma phagocytophilum (A. phagocytophilum), and 19 control dogs were evaluated and compared retrospectively. The aim of our study was to ... determine statistically significant differences of selected parameters between groups of patients, divided according to the immunofluorescence (IFA) titres, in attempt to improve current diagnostic and treatment criteria. Exposure to A. phagocytophilum was confirmed by IFA and infection by PCR. Based on the results, the dogs were divided into 8 groups (6 groups of seropositive dogs according to the antibody titre, 1 group of PCR positive dogs, and a control group). Selected parameters were compared between groups. Thrombocytopenia wasconfirmed to be the most prominent haematological change in IFA and/or PCR positive dogs. There were no statistically significant differences in clinicaland haematological observations between groups of different IFA titre but clear overall differences between each IFA and PCR positive groups compared to the control group. Our results showed the necessity of introducingadditional diagnostic procedures in clinical practice, since antibody titre and haematological parameters are not sufficient to confirm the clinical relevance of exposure to A. phagocytophilum in a particular patient.Source: Veterinary Microbiology. - ISSN 0378-1135 (Vol. 149, issue 1/2, 2011, str. 172-176)Type of material - article, component partPublish date - 2011Language - englishCOBISS.SI-ID - 28169945
Author
Ravnik Verbič, Urška |
Tozon, Nataša |
Strašek, Katja |
Avšič-Županc, Tatjana
Topics
Dog Diseases |
Anaplasmosis |
Diagnosis |
Blood |
Veterinary |
Anaplasma |
Isolation And Purification |
Thrombocytopenia |
Polymerase Chain Reaction |
Fluorescent Antibody Technique |
Urinalysis |
Retrospective Studies |
Dogs |
Polimerazna, verižna reakcija |
Anaplazmoza |
Pes, bolezni |
Trombocitopenija |
Anaplasma |
Fluorescentna tehnika za protitelesa |
Urin, analiza |
Retrospektivne študije |
Psi
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Database name | Field | Year |
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Ravnik Verbič, Urška | 29350 |
Tozon, Nataša | 13328 |
Strašek, Katja | 25989 |
Avšič-Županc, Tatjana | 10331 |
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