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  • Resni neželeni učinki zdravljenja kronične levkemije z zaviralci tirozinske kinaze - prikaz primerov in pregled literature = Severe adverse effects associated with tyrosine kinase inhibitors therapy in chronic myeloid leukaemia - case reports and literature review
    Krstanoska, Frosina ...
    Background: Chronic myeloid leukaemia is a clonal myeloproliferative disorder of myeloid progenitor cells. The availability of moleculartargeted therapy with tyrosine kinase inhibitors has changed ... the course and treatment for patients with chronic myeloid leukemia. The long-term follow-up of adverse events amongst the kinase inhibitors played role in forming decision- making algorithms for the use of this highly effective group of therapeutics. Patients and methods: In this paper, four CML patients are presented, treated with different tyrosine kinase inhibitors. Haematologic toxicity of kinase inhibitors is the most frequent adverse effect; however, non-haematological adverse effects should also not be neglected. Conclusions: Tyrosine kinase inhibitors have changed the therapy of CML, the treatment of these patients isa long-term process. Therefore, to know adverse effects is the matter of great importance in order to promptly recognise them and treat them properly.
    Source: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 80, št. 5, maj 2011, str. 413-421)
    Type of material - article, component part
    Publish date - 2011
    Language - slovenian
    COBISS.SI-ID - 28448473

    Link(s):

    http://szd.si/user_files/vsebina/Zdravniski_Vestnik/2011/maj/413-21.pdf
    Digitalna knjižnica Slovenije - dLib.si

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