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  • Comparison of rubella virus- and herpes virus-associated anterior uveitis : clinical manifestations and visual prognosis
    Wensing, Barbara ...
    Purpose: To compare the clinical characteristics and visual prognosis of patients with anterior uveitis (AU) and intraocular fluid analysis positive for rubella virus (RV), herpes simplex virus ... (HSV), or varicella zoster virus (VZV). DESIGN: Retrospective, observational study. Participants: The study included 106 patients with AU and positive polymerase chain reaction (PCR) results, Goldmann-Witmer coefficients (GWCs), or both, for RV (n = 57), HSV (n= 39), or VZV (n = 10). Mezhods: Clinical records of the included patients were analyzed retrospectively; demographic constitution, ophthalmologic characteristics, and visual prognosis were compared. Main outcome measures: Age, gender, and diverse clinical and laboratory characteristics, including course and laterality of AU; prevalence of positive results for PCR, GWC, or both; conjunctival redness; corneal edema; history of keratitis; presence of keratic precipitates; synechiae; heterochromia; and grade of inflammation. In addition, complications and visual acuity at 1 and 3 years of follow-up were recorded. Results: All 3 types of viral AU were characterized by unilateral involvement (80%-97%). Rubella virus AU was characterized by younger age at onset and chronic course and typically was associated with cataract at presentation. Heterochromia was present in 23% of RV AU patients. Anterior uveitis associated with HSV or VZV occurred characteristically in older patients and frequently followed an acute course. Clinical features associatedwith herpetic AU included conjunctival redness, corneal edema, history of keratitis, and development of posterior synechiae. Herpes simplex virus AU often had severe anterior chamber inflammation, whereas the presence of vitritis was more common in RV AU and VZV AU. The prevalence of documented intraocular pressure (IOP) of more than 30 mmHg (25%-50%; P = 0.06) and development of glaucoma (18%-30%; P = 0.686) were similar in all 3
    Source: Ophthalmology. - ISSN 0161-6420 (Vol. 118, issue 10, 2011, str. 1905-1910)
    Type of material - article, component part
    Publish date - 2011
    Language - english
    COBISS.SI-ID - 29417433
    DOI

source: Ophthalmology. - ISSN 0161-6420 (Vol. 118, issue 10, 2011, str. 1905-1910)
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