Krajnc, Mitja, zdravnik, 1980- ; Zavratnik, Andrej
Insuficienca nadledvičnih žlez je posledica prizadetosti hipotalama - hipofizno-adrenalne osi. Primarna oblika, Addisonova bolezen, je redka in je najpogosteje posledica avtoimunskega adrenalitisa. ...Na pogostejšo terciarno insuficienco nadledvičnic moramo pomisliti pri bolnikih, ki so bili dalj časa zdravljeni z glukokortikoidi. Simptomi in znaki bolezni so pestri in velikokrat nespecifični, nanjo je potrebno pomisliti zlasti ob značilnih kliničnih podatkih hiperpigmentacije, kronična utrujenost, slabost, hiponatremija in hiperkaliemija. Pravočasna prepoznava je posebej pomembna pri adrenalni krizi, ki se lahko kaže s šokom in zahteva takojšnje zdravljenje. Bolezen diagnosticiramo predvsem s hormonskimi in morfološkimi preiskavami. Zdravljenje kronične insufucuence temelji na hormonskem nadomeščanju, pri čemer je pri izpostavljenosti večjemu stresu potrebno povišanje odmerka glukokortikoidov.
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