-
High prevalence of Gammapapillomaviruses (Gamma-PVs) in pre-malignant cutaneous lesions of immunocompetent individuals using a new broadspectrum primer system, and identification of HPV210, a novel Gamma-PV typeBolatti, Elisa ...Genus Gammapapillomavirus (Gamma-PV) is the most diverse and largest clade within the Papillomaviridae family. A novel set of degenerate primers targeting the E1 gene was designed and further used in ... combination with the well-known CUT PCR assay to assess HPV prevalence and genus distribution in a variety of cutaneous samples from 448 immunocompetent individuals. General HPV, Gamma-PV and mixed infections prevalence were significantly higher in actinic keratosis with respect to benign and malignant neoplasms, respectively (p=0.0047, p=0.0172, p=0.00001). Gamma-PVs were significantly more common in actinic keratosis biopsies than Beta- and Alpha-PVs (p=0.002). The full-length genome sequence of a novel putative Gamma-PV type was amplified by 'hanging droplet' long-range PCR and cloned. The novel virus, designated HPV210, clustered within species Gamma-12. This study provides an additional tool enabling detection of HPV infections in skin and adds new insights about possible early roles of Gamma-PVs in the development of cutaneous malignant lesions.Source: Virology. - ISSN 0042-6822 (Vol. 525, 2018, str. 182-191)Type of material - article, component partPublish date - 2018Language - englishCOBISS.SI-ID - 33999065
Author
Bolatti, Elisa |
Hošnjak, Lea |
Chouhy, Diego |
Re-Louhau, Maria F. |
Casal, Pablo E. |
Bottai, Hebe |
Kocjan, Boštjan |
Stella, Emma J. |
Gorosito, Mario D. |
Sanchez, Adriana |
Fernandez Bussy, Ramón |
Poljak, Mario, 1965- |
Giri, Adriana A.
Topics
gammapapillomavirus |
actinic keratosis |
genomic characterization |
gammapapillomavirus |
aktinična keratoza |
genomska karakterizacija
Shelf entry
Permalink
- URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year | Impact factor | Edition | Category | Classification | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Select the library membership card:
DRS, in which the journal is indexed
Database name | Field | Year |
---|
Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
---|---|
Bolatti, Elisa | |
Hošnjak, Lea | 38525 |
Chouhy, Diego | |
Re-Louhau, Maria F. | |
Casal, Pablo E. | |
Bottai, Hebe | |
Kocjan, Boštjan | 23430 |
Stella, Emma J. | |
Gorosito, Mario D. | |
Sanchez, Adriana | |
Fernandez Bussy, Ramón | |
Poljak, Mario, 1965- | 11622 |
Giri, Adriana A. |
Select pickup location:
Material pickup by post
Notification
Subject headings in COBISS General List of Subject Headings
Select pickup location
Pickup location | Material status | Reservation |
---|
Please wait a moment.