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Atrosklerotične mRNA v plazmi = Atherosclerotic mRNA in the plasma [El. vir] : neinvazivna analiza izražanja genov žilne stene : non-invasive analysis of gene expression in vascular bedsČerne, DarkoZunajcelične nukleinske kisline so nukleinske kisline (DNA, mRNA, miRNA, mitohondrijska DNA), ki se nahajajo v plazmi in drugih bioloških vzorcih zunaj celic. V zadnjem času je njihova analiza ... postala pomembno raziskovalno orodje tudi na področju preučevanja ateroskleroze. Omogoča diagnostiko akutnega koronarnega sindroma in prognostična sklepanja, ocenjevanje tveganja za razvoj ateroskleroze in njenih akutnih ishemičnih zapletov, zgodnjo neinvazivno diagnostiko bolezni in preučevanje patoloških mehanizmov aterogeneze in vivo, preučevanje različnih dejavnikov v zdravljenju ateroskleroze in tudi edinstveno istočasmo merjenje koncentracije mRNA in njihovih proteinov v plazmi. V prispevku so predstavljeni primeri uporabe, s posebnim poudarkom na analizi mRNA v plazmi.Source: 6. Jesenovčevi dnevi - raziskovalni dnevi laboratorijske biomedicine, 20. september 2014, Ljubljana [Elektronski vir] : zbornik predavanj (Str. 76-84)Type of material - conference contributionPublish date - 2014Language - slovenianCOBISS.SI-ID - 3715185
Author
Černe, Darko
Topics
Ateroskleroza |
mRNA v plazmi |
izražanje gena v žilni steni |
neinvaziven
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Černe, Darko | 15099 |
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