Muscle hypertrophy and muscle strength [Elektronski vir] : dependent or independent variables? : a provocative review
Reggiani, Carlo ; Schiaffino, Stefano
The question whether the muscle hypertrophy induced by resistance training, hormone administration or genetic manipulation is accompanied by a proportional increase in muscle strength is still open. ...This review summarizes and analyses data obtained in huma n and rodent muscles in studies that have monitored in parallel changes in muscle size and changes in muscle force, measured in isometric contractions in vivo, in isolated muscles ex vivo (in rodents ) and in single muscle fibers. Although a general positiv e relation exists among the two variables, a number of studies show a clear dissociation with increase of muscle size with no change or even decrease in strength and, vice versa, increase in strength without increase in size. The possible mechanisms of suc h dissociation , which involves neural motor control and /or cellular and molecular adaptations of muscle fibers, are briefly discussed .
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