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13.
Okvara ledvic - vrednotenje in izziv za laboratorijsko medicino = Acute kidney injury - assessment and the role of laboratory medicine in monitoring injury and function of kidney
Skitek, Milan ; Jerin, Aleš
Akutno okvaro ledvic (AOL) razvije okoli 20% bolnikov v bolnišničnih urgentnihin intenzivnih oddelkih. Stopnja okvare in disfunkcije ledvic je povezana z višjo umrljivostjo in je neodvisen vzrok za ...smrt bolnika. Najpogostejša oblika intrinzične-renalne AOL je ishemija, povezana z hemodinamskimi motnjami, poškodbami parenhima in imunološkimi mehanizmi, ki sovključeni v začetek procesa in poslabšanje AOL z intenzivnim proinflamatornim stanjem. Obravnavana bo nova klasifikacija stopenjske AOL v luči konvencionalnih in novejših biooznačevalcev ledvične (dis)funkcije in okvare. Izziv za laboratorijsko medicino predstavljajo novejši biooznačevalci,bolj občutljivi in specifični za bolj točno, zanesljivo in zgodnejšo napoved AOL.
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