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Zastrupitev z etilenglikolom = Ethylene glycol intoxication
Vodošek Hojs, Nina ; Ekart, Robert, 1967- ; Svenšek, Franc
Zastrupitve z etilenglikolom so dokaj redke. Etilenglikol je sam po sebi malo toksičen, hudo zastrupitev povzročajo predvsem njegovi presnovni produkti. Prikazani primer obravnava značilno klinično ...sliko (nevrološka, kardiopulmonalna in ledvična faza) in laboratorijske rezultate (povišana serumska osmolalnost, povišana osmolalna vrzel, metabolična acidoza s povišano anionsko vrzeljo, kristali kalcijevega oksalata v urinu) ob zastrupitvi z etilenglikolom. Hitra prepoznava je nujna, saj sta obolevnost in smrtnost po zastrupitvi visoki. Zdravljenje vključuje vzdrževanje dihalne poti, dihanja in krvnega obtoka, infuzijo bikarbonata, dajanje antidota (etanol, fomepizol), hemodializo, včasih tudi zdravljenje s kofaktorji presnove etilenglikola (tiamin, piridoksin, magnezij).
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