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Alkohol in zdravila = Alcohol and medicinesPeterlin-Mašič, LucijaEtanol je ena najbolj uporabljenih legalnih psihoaktivnih snovi z visokim potencialom za zlorabo. Pri hkratnem uživanju alkohola in zdravil lahko pride do medsebojnega delovanja (interakcij) med ... etanolom in učinkovinami. Starostniki pogosteje hkrati uživajo alkohol in zdravila, zato je tveganje za neželene učinke pri njih veliko. Pri hkratnem uživanju etanola in zdravil lahko pride do farmakokinetičnih ali farmakodinamičnih interakcij. Pri farmakokinetičnih interakcijah etanol neposredno vpliva na normalno presnovo učinkovine in na njeno koncentracijo v krvi. Farmakodinamične interakcije pa se nanašajo predvsem na seštevanje zaviralnih učinkov etanola in učinkovin na osrednji živčni sistem, zato obstaja nevarnost prekomerne sedacije pri učinkovinah, ki zaviralno delujejo na osrednje živčevje. V realnosti so interakcije med etanolom in učinkovinami pogosto kompleksne, saj smo lahko hkrati izpostavljeni etanolu ter več učinkovinam in drugim snovem. V preglednem članku smo se osredotočili na predstavitev delovanja etanola na organizem ter na znanstveno razlago znanih farmakokinetičnih in farmakodinamičnih interakcij med etanolom in učinkovinami.Source: Farmacevtski vestnik : strokovno glasilo slovenske farmacije = pharmaceutical journal of Slovenia. - ISSN 0014-8229 (Letn. 69, št. 2, 2018, str. 81-91)Type of material - article, component partPublish date - 2018Language - slovenianCOBISS.SI-ID - 4506225
Author
Peterlin-Mašič, Lucija
Topics
Alkohol |
Zdravila |
interakcije učinkovin |
etanol |
kombinacije učinkovin
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source: Farmacevtski vestnik : strokovno glasilo slovenske farmacije = pharmaceutical journal of Slovenia. - ISSN 0014-8229 (Letn. 69, št. 2, 2018, str. 81-91)
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Peterlin-Mašič, Lucija | 19317 |
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