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Tumorji hipofize - prikaz primerov = Pituitary tumors - case reportKšela, Urša ; Zemljič, Eva, 1976-Tumorji hipofize so neoplazme, ki zrastejo v turškem sedlu ali njegovi neposredni bližini. V veliki večini so benigni in nastanejo iz celic hipofize ali iz ostankov kraniofaringealnega voda. ... Najpogostejši so hipofizni adenomi, klinično pomembna sta 2/100.000 na leto. Glede na velikost jih delimo na mikroadenome, če merijo v premeru manj kot 1 cm, in makroadenome, če so večji kot 1 cm. Lahko so klinično hormonsko aktivni ali nemi, približno tretjina adenomov je hormonsko neaktivnih. Klinične znake in simptome delimo na lokalne, ki so posledica pritiska na okolne strukture v primeru invazivne rasti (glavobol, izpad vidnega polja, diabetes insipidus...), in na sistemske, ki nastanejo zaradi hormonskih motenj. Ob sumu na tumor v hipotalamo-hipofiznem območju opravimo morfološke preiskave, funkcionalne preiskave vida in usmerjene hormonske preiskave. Med slikovnimi preiskavami je najpomembnejša magnetna resonanca. Hormonski testi opredelijo funkcijsko rezervo hipofize, z ustreznimi testi pa potrdimo klinični sum čezmernega izločanja hipofiznih hormonov. Hormonsko neaktivne incidentalome opazujemo. Večje hormonsko neaktivne adenome, ki povzročajo lokalne in sistemske simptome, operativno odstranjujemo po transfenoidalni poti. Z zdravili zdravimo primarno le hormonsko aktivne tumorje, ki izločajo prolaktin, pri vseh ostalih hormonsko aktivnih adenomih je indicirana operativna odstranitev. Če je hipofizni tumor ali njegovo zdravljenje povzročilo nastanek hipopituitarizma je potrebno manjkajoče hormone nadomeščati.Source: [Zbornik predavanj] (Str. 135-137)Type of material - conference contribution ; adult, seriousPublish date - 2013Language - slovenianCOBISS.SI-ID - 4677695
Author
Kšela, Urša |
Zemljič, Eva, 1976-
Topics
prolaktinom |
hormonsko neaktivni adenom |
panhipopituitarizem |
hipofiza |
tumorji
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Database name | Field | Year |
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Kšela, Urša | 92111 |
Zemljič, Eva, 1976- | 92112 |
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