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Invasive cell grading as a predictive factor of occult metastasis in oral cavity and oropharynx carcinoma = Stopnja celične invazivnosti kot napovedni dejavnik za okultne zasevke karcinoma ustne votline in ustnega žrelaRussolo, Mario ; Tirelli, Giovanni ; Giacomarra, VittorioThere is still debate as to the treatment of a neck with no clinical evidence of nodal metastases in patients suffering from carcinoma of the oral cavity and oropharynx. There is a high incidence of ... occult metastases and the appearance of local metastases following treatment limitad to the tumor leads to sharp drop in survival rates. Imaging diagnostic examinations such as echography, computerised tomography and magnetic resonance imaging have high diagnostic accuracy, but by that mean it is not possible to evaluate whether occult metastases and neoplastic cell in transit are present or not. In an attempt to rationalise treatment of the neck with no clinical evidence of nodal metastases we have evaluated the efficiency of invasive cell grading as a prognostic factor of occult metastases. The invasive cell grading score was evaluated in a pre-surgery biopsy of the invasive border of the carcinoma and postoperatively in the surgical specimen of the neck dissection. A comparison between the invasive cell grading and the condition of the lymph nodes showed that there was a statistically significant correlation between the invasive cell grading category and the presence of local occult metasteses.Source: 2. kongres otorinolaringologov : zbornik predavanj (Let. 35, Suppl. 6, 1996, str. 107-111)Type of material - conference contributionPublish date - 1996Language - englishCOBISS.SI-ID - 4975833
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