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Zastrupitev z gama-hidroksibutiratom (GHB) - predstavitev primera = Gamma-hydroxybutyrate (GHB) intoxication - case reportCestar, Iva ; Prosen, Gregor, 1979-Gama-hidroksibutirat je psihoaktivna substanca, v zadnjih 20 letih vedno pogosteje prisotna kot klubska droga na rejvih, znan je tudi kot droga za posilstvo na zmenkih. Je brez barve, vonja, nekoliko ... slanega okusa, pojavlja se v obliki tekočine, praška, tablet in kapsul. Sprva so GHB uporabljali kot splošni anestetik, znana je uporaba v bodybuildingu, za hujšanje, ponekod je registriran kot zdravilo za narkolepsijo in katapleksijo ter za zdravljenje odvisnosti od alkohola. Naravno je prisoten v CŽS kot prekurzor in metabolit GABA. Zloraba GHB je najpogostejša med mladimi moškimi na zabavah. Zastrupitev se kaže predvsem z depresijo CŽS in respiratornega sistema, z različnimi simptomi od blage sedacije do globoke kome in respiratornega zastoja. Simptomi zastrupitve navadno izzvenijo po 6 do 12 urah. GHB ima kratko razpolovno dobo in se hitro eliminira iz telesa, zato je zastrupitev težko dokazati. Pri diagnozi zastrupitve nam pomaga anamneza in heteroanamneza, na zastrupitev moramo pomisliti, diferencialno diagnostično pa je potrebno izključiti druge možne vzroke za motnje zavesti. Terapija je simptomatska, specifičen antidot ne obstaja.Source: Urgentna medicina : izbrana poglavja 2013 : zbornik = Emergency medicine : selected topics [2013] : proceedings (Str. 205-207)Type of material - conference contributionPublish date - 2013Language - slovenianCOBISS.SI-ID - 512310840
Author
Cestar, Iva |
Prosen, Gregor, 1979-
Topics
zastrupitev |
urgentna medicina |
droga |
terapija |
psihoaktivna substanca |
GHB
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Cestar, Iva | |
Prosen, Gregor, 1979- | 37131 |
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