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Potential interactions between cannabinoids and estrogens in common diseases = Možne interakcije med kanabinoidi in estrogeni pri pogostih boleznihHojnik, Marko, 1990- ; Dobovišek, Luka ; Ferk, PoloncaPred kratkim so odkrili prve molekularne povezave med kanabinoidnim sistemom in estrogeni. Preučevanje medsebojnega učinkovanja je zanimivo predvsem zato, ker bi lahko privedlo do novih ... farmakoterapevtskih pristopov, zlasti pri boleznih, kjer sta oba molekularna sistema vpletena v patofiziologijo bolezni. Članek predstavlja pregled vloge kanabinoidnega sistema in estrogenov pri osteoporozi, aterosklerozi in raku ter potencialne koristi medsebojne povezave obeh sistemov pri farmakoterapiji teh bolezni. Po obsežnem pregledu literature utemeljeno sklepamo na verjetno součinkovanje med kanabinoidnim sistemom in estrogeni, vendar ustreznih neposrednih študij na molekularnem nivoju v literaturi nismo zasledili. Z rezultati nedavne lastne raziskave na primarnih kulturah človeških osteoblastov smo prvi pokazali na morebitno molekularno součinkovanje med navedenima sistemoma. Potrebne so nadaljnje raziskave, ki bodo natančno preučile molekularno součinkovanje ter koristnosti in varnost posameznih kombinacij estrogenov in kanabinoidov v patogenezi oz. farmakoterapiji osteoporoze, ateroskleroze, rakavih in drugih pogostih obolenj.Source: Acta medico-biotechnica : AMB. - ISSN 1855-5640 (Vol. 7, [no.] 2, 2014, str. 23-29)Type of material - article, component part ; adult, seriousPublish date - 2014Language - englishCOBISS.SI-ID - 512465976
Author
Hojnik, Marko, 1990- |
Dobovišek, Luka |
Ferk, Polonca
Topics
estrogeni |
kanabinoidi |
osteoporoza |
ateroskleroza |
rak (medicina) |
estrogens |
cannabinoids |
osteoporosis |
atherosclerosis |
cancer
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Hojnik, Marko, 1990- | 39347 |
Dobovišek, Luka | 52511 |
Ferk, Polonca | 22621 |
Source: Personal bibliographies
and: SICRIS
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