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Synthesis of 2-amino-7,8-dihydro-6(5H)quinazolinone, 2,4-diamino-7,8-dihydro-6(5H)-quinazolinone, 5,6,7,8-tetrahydro-2,6-quinazolinediamine and 5,6,7,8-tetrahydro-2,4,6-quinazolinetriamine derivatives
Marinko, Petra, 1970- ...
N-(2-amino-5,6,7,8-tetrahydro-6-quinazolinyl)acetamide (9) and N-(2,4-diamino-5,6,7,8-tetrahydro-6-quinazolinyl)acetamide (6) were synthesized from N-(4-oxocyclohexyl)acetamide (5) as novel ...peptidomimetic building blocks. With similar purpose, N-(6-oxo-5,6,7,8,-tetrahydro-2quinazolinyl)acetamide (18) and N-[2-(acetylamino)-6-oxo-5,6,7,8-tetrahydro-4-quinazolinyl]acetamide (14) were prepared from cyclohexane-1,4-dione monoethylene ketal (11).
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