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Bakterijska poslabšanja kronične obstruktivne pljučne bolezni (KOPB) in občutljivost za antibiotike = Bacterial exacerbations of chronic obstructive pulmonary disease (COPD) and sensitivity for antibioticsDebeljak, Andrej, 1940- ; Mušič, Ema ; Kumelj, MarkoBackground. The aim of our study was to find out bacterial species responsablefor acute bacterial exacerbations and their susceptibility to antibiotics in patients with COPD admitted to our hospital ... in the year 1995. Methods. Retrospectively we analysed sputum bacteriologic cultures and sensitivities in 1291 patients with severe exacerbations of COPD. Among them there were 142 males and 49 females, aged 70+-9. Patients were referred to hospital due to home management failure. Results. Two hundred forty-nine potential pathogens were recovered during 315 bacterial exacerbations. We confirmed Streptococcus pneumoniae in 78 (41%), Haemophilus influenzae and parainfluenzae in 53 (28%), Moraxella catarrhalis in 31 (16%), Pseudomonas aeruginosa in 43 (23%) and Staphylococcus aresus in 32 (17%) of patients. Clindamycin, cefotaxim, amoxicillin, amoxicillin/clavulanic acid, penicillin were in vitro active against Streptococcus pneumoniae in 73-60 cases (99%-81%). Ciprofloxacin, pefloxacin, cefuroxim, ampicillin/sulbactam, amoxicallin/clavulanic acid and azytromycin were efficient in vitro against Haemophilus species in 48-41 cases (100%-85%). Amoxicillin/clavulanic acid, ampicillin/sulbactam, cefotaxim, cefuroxim and roxitromycin were in vitro effective against Moraxella catarrhalis in all 28 case (10%). Azytromycin, ciprofloxacin and pefloxacin were active to the same bacteriain 27-25 cases (96%-89%). Pseudomonas aeruginosa was in vitro sensitive forceftazidime, imipenem, azlocillin, amikacin and ciprofloxacin in 36-25 cases (88%-61%). Efficiency for Staphylococcus aureus was in 30-17 cases (100%-57%) for vancomycian, netilmicin, ceftazidime, cefazolin, cefuroxime, and gentamycin.(Abstract truncated at 2000 characters.)Source: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 67, št. 5, maj 1998, str. 285-288)Type of material - article, component partPublish date - 1998Language - slovenianCOBISS.SI-ID - 7910105
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source: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 67, št. 5, maj 1998, str. 285-288)
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Debeljak, Andrej, 1940- | 01726 |
Mušič, Ema | 00288 |
Kumelj, Marko | 10685 |
Source: Personal bibliographies
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