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The place of chemotherapy in the evolving treatment landscape for patients with HR-positive/HER2-negative MBCTwelves, Chris ...Endocrine therapy (ET) for the treatment of patients with hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR-positive/HER2-negative) metastatic breast cancer (MBC) has ... changed markedly over recent years with the emergence of new ETs and the use of molecularly targeted agents. Cytotoxic chemotherapy continues, however, to have an important role in these patients and it is important to maximize its efficacy while minimizing toxicity to optimize outcomes. This review examines current HR-positive/HER2-negative MBC clinical guidelines and addresses key questions around the use of chemotherapy in the face of emerging therapeutic options. Specifically, the indications for chemotherapy in patients with HR-positive/HER2-negative MBC and the choice of optimal chemotherapy are discussed.Source: Clinical breast cancer. - ISSN 1526-8209 (Vol. 22, iss. 3, 2022, str. 223-234)Type of material - article, component partPublish date - 2022Language - englishCOBISS.SI-ID - 87554819
Author
Twelves, Chris |
Bartsch, Rupert |
Ben-Baruch, Noa Efrat |
Borštnar, Simona, 1967- |
Dirix, Luc Yves |
Tesarova, Petra |
Timcheva, Constanta |
Zhukova, Lyudmila |
Pivot, Xavier
Topics
kemoterapija |
citotoksičnost |
hormonsko pozitivni rak |
metastatski rak dojke |
chemotherapy |
cytotoxic |
HR positive |
metastatic breast cancer
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Twelves, Chris | |
Bartsch, Rupert | |
Ben-Baruch, Noa Efrat | |
Borštnar, Simona, 1967- | 16303 |
Dirix, Luc Yves | |
Tesarova, Petra | |
Timcheva, Constanta | |
Zhukova, Lyudmila | |
Pivot, Xavier |
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