Faculty of Pharmacy, Lj. (FFALJ)
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Gensko zdravljenje sladkorne bolezni tipa 1 [Elektronski vir]Valič, Tjaša, farmacevtkaSladkorna bolezen tipa 1 je kronična avtoimunska bolezen, ki jo povzroči uničenje pankreatičnih celic β in vodi v življenje ogrožajočo hiperglikemijo. K nastanku bolezni prispevajo številni genetski ... in okoljski dejavniki v različnih kombinacijah, kar predstavlja glavni izziv pri iskanju učinkovitega zdravila. V tem članku je najprej predstavljeno patogenetsko ozadje bolezni, sledita pregled potencialnih imunoloških intervencij, s katerimi bi lahko preprečili nastanek bolezni ali spremenili njen potek, in pregled uporabe celičnih terapij. Glavni poudarek članka je na genskem zdravljenju: osnovnemu konceptu in možnim dostavnim sistemom za vnos genov sledi nekaj primerov uspešnih poskusov genskega zdravljenja na živalskih modelih, ki nas lahko navdajajo z upanjem, da bo sladkorna bolezen tipa 1 nekoč ozdravljiva.Source: Placebo [Elektronski vir] : strokovna revija DŠFS in ŠSSFD. - ISSN 2820-5014 (št. 1, sep. 2022, str. 40-44)Type of material - e-article ; adult, seriousPublish date - 2022Language - slovenian, englishCOBISS.SI-ID - 122913539
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