Wegenerjeva granulomatoza v področju glave in vratu = Wegener's granulomatosis in the head and neck region
Zidar, Nina, 1960- ; Trček, Ciril, zdravnik
Wegener's granulomatosis is a systemic disease characterized by necrotizing vasculitis and granuloma formation in the upper and lower respiratory tracts, and glomerulonephritis. The vast majority of ...patients have antineutrophil cytoplasmic antibodies in the serum with the characteristic cytoplasmic pattern. Early detection of Wegener's granulomatosis is essential to avoid significant morbidity and mortality characteristic of fully developed disease.However, in early phases of the disease only the upper respiratory tract can be affected, clinical and histological features can be nonspecific, and antineutrophil cytoplasmic antibodies not present. In this paper, we emphasise the significance of clinical, histological, and serological parameters in early detection of Wegener's granulomatosis.
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