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  • Smernice za zdravljenje zastrupitev s paracetamolom = Guidelines for paracetamol poisoning treatment
    Šarc, Lucija, 1968- ...
    Paracetamol overdose results in an accumulation of the reactive, hepatotoxic metabolite N-acetyl-p-benzoquinoneimin (NAPKQI) which can cause serious liver injury. Recognition of paracetamol overdose, ... hepatotoxicity risk estimation and early treatment are crutial in paracetamol poisoniong management. In ingestion of potential hepatotoxic dose of paracetamol decontamination and early treatment with N-acetylcysteine (NAC) are indicated. Both, 20-hours intravenous and 72-hurs oral regimes of NAC administration are successful. By antidote regime selection we should consider patient condition and time after paracetamol overdose. In severe hepatotoxicity, criteria for liver transplantation should be regularly evaluated and mechanisms for liver transplantation must be activated in time.
    Source: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 83, št. 3, mar. 2014, str. 201-208)
    Type of material - article, component part ; adult, serious
    Publish date - 2014
    Language - slovenian
    COBISS.SI-ID - 31311321

    Link(s):

    http://vestnik.szd.si/index.php/ZdravVest/article/view/974
    Digitalna knjižnica Slovenije - dLib.si

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