Miklošič Library FPNM, Maribor (PEFMB)
-
Matematično modeliranje vpliva fosforilacije regulatornih verig lahkega miozina na mehansko napetost v gladkih mišicah dihalnih poti : magistrsko deloDobovišek, AndrejV magistrskem delu z metodo matematičnega modeliranja preučujemo vpliv procesov fosforilacije in defosforilacije verig lahkega miozina (MLC) na mehansko napetost v gladkih mišicah dihalnih poti. Kot ... izhodišče za raziskave privzamemo model Rembolda (1991), ki omogoča izračun mehanske napetosti v gladkih mišicah, model pa nadgradimo z novim matematičnim opisom aktivnosti encimov kinaze (MLCK) 10 fosfataze (MLCP) lahkih verig miozina, ki regulirata procesa fosforilacije 10 defosforilacije MLC. Naredimo naslednji dopolnitvi: 1) matematični izraz za aktivnost MLCK, dobljen na osnovi prilagajanja matematične odvisnosti eksperimentalnim podatkom, nadomestimo z matematičnim modelom interakcij med kalcijevimi ioni, kalmodulinom in MLCK, ki ga predlagajo Kato in sod. (1984). 2) Na osnovi Michaelis-Mentenine encimske kinetike izdelamo popolnoma nov matematični opis aktivnosti MLCP, pri čemer defosforilacijo MLC obravnavamo kot encimsko reakcijo z dvema substratoma. Ugotovimo, da se modelne napovedi deleža fosforiliranih prečnih mostičkov in mehanske napetosti v odvisnosti od koncentracije kalcija, izračunane z našim modelom, z ustreznimi eksperimentalnimi podatki ujemajo bolje kakor napovedi prvotnega modela. Napovedali smo tudi časovno zakasnitev razvoja mehanske napetosti za dvofaznim kalcijevim signalom.Type of material - master's thesis ; adult, seriousPublication and manufacture - Maribor : [A. Dobovišek], 2008Language - slovenianCOBISS.SI-ID - 16059656
Author
Dobovišek, Andrej
Other authors
Brumen, Milan, 1951- |
Fajmut, Aleš |
Marhl, Marko
Topics
fizika |
matematični model |
lahka veriga miozina |
kinaza lahkih verig miozina |
fosfaza lahkih verig miozina |
mehanska napetost |
gladka mišica |
magistrska dela
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Call number – location, accession no. ... |
Copy status | Reservation |
---|---|---|
D MAG 0000000053 DOBOVIŠEK A. Matematično IN: 920080042 D MAG 53 DOBOVIŠEK A. Matematično IN: 920080042 |
available - reading room
|
![loading ... loading ...](themes/default/img/ajax-loading.gif)
![loading ... loading ...](themes/default/img/ajax-loading.gif)
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Shelf entry
Permalink
- URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year | Impact factor | Edition | Category | Classification | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Select the library membership card:
If the library membership card is not in the list,
add a new one.
DRS, in which the journal is indexed
Database name | Field | Year |
---|
Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
---|---|
Dobovišek, Andrej | 26447 |
Brumen, Milan, 1951- | 05483 |
Fajmut, Aleš | 19553 |
Marhl, Marko | 13159 |
Source: Personal bibliographies
and: SICRIS
Select pickup location:
Material pickup by post
Delivery address:
Address is missing from the member's data.
The address retrieval service is currently unavailable, please try again.
By clicking the "OK" button, you will confirm the pickup location selected above and complete the reservation process.
By clicking the "OK" button, you will confirm the above pickup location and delivery address, and complete the reservation process.
By clicking the "OK" button, you will confirm the address selected above and complete the reservation process.
Notification
Automatic login and reservation service currently not available. You can reserve the material on the Biblos portal or try again here later.
Subject headings in COBISS General List of Subject Headings
Select pickup location
The material from the parent unit is free. If the material is delivered to the pickup location from another unit, the library may charge you for this service.
Pickup location | Material status | Reservation |
---|
Reservation in progress
Please wait a moment.
Reservation was successful.
Reservation failed.
Reservation...
Membership card:
Pickup location:
Miklošičeva knjižnica - FPNM bo od 17. 6. 2024 do 30. 9. 2024 odprta vsak dan od ponedljka do petka od 8.00 do 14.00.
Srečno.
Kolektiv Miklošičeve knjižnice - FPNM