Background: In ABO-incompatible (ABOi) solid organ transplantation, the minimization and management of isoagglutinin (IA) against donor ABO antigens between before and two weeks after transplantation ...is important for preventing hyper-acute rejection. Several factors that can affect the IA titer have been reported. This is the first study to evaluate whether there are IA titer differences between kidney transplantation (KT) and liver transplantation (LT) recipients.
Methods: Thirty-eight KT and 32 LT type O recipients, who underwent ABOi KT or LT between March 2013 and March 2018, were enrolled consecutively. The IgM IA and IgG IA titers of the LT and KT recipients at different time points (initial, operation day day-0, postoperative one week, four weeks, and one year) were evaluated.
Results: The LT recipients showed higher initial IgG IA titers than the KT recipients (P=0.01). This higher titer in the LT recipients persisted during the critical phase (from before transplantation to postoperative one week).
The IgG and IgM IA titers were similar in the KT and LT recipients at postoperative four weeks.
Conclusion: The difference in IA titer between the underlying diseases should be considered in the desensitization protocol before ABOi SOT. (Korean J Blood Transfus 2021;32:112-122) KCI Citation Count: 0
학업 스트레스 개입 변인을 탐색하고자 학업정신건강에 대한 학업요구와 학업자원의 영향이 스트레스마인드셋에 따라 달라지는지 확인하였다. 직무스트레스 분야 대표 이론인 직무요구-자원모형(Job Demands-Resources Model)을 적용하여 고등학생 1, 2학년 391명을 대상으로 학업 환경 관점에서학업요구와 자원을 구성하여 구조방정식으로 검증하였다. ...스트레스 마인드셋 저집단은 학업요구가 학업소진만을 유의하게 설명하는 반면, 스트레스 마인드셋 고집단은 학업자원이 학업소진과 학업열의를 모두 유의하게 설명하는 것으로 나타났다. 고교생의 학업정신건강 증진을 위하여 스트레스 마인드셋을 증진시킬수 있는 스트레스 관리 방안이 필요함을 이론 및 경험적으로 확인하였다는 점에서 의의가 있다. Background: This study aimed to identify stress mindset as an intervention factor for academic stress management within the framework of the Job Demands-Resources Model. We investigated the role of a stress mindset in the relationship between academic demands, resources, burnout, engagement as academic mental health.
Methods: From the perspective of academic interpersonal perceptions, 391 first- and second-year high school students were analyzed using a structural equation model consisting of observed variables with demands and resources from parents, teachers, and peers.
Results: The low-stress mindset group showed a significant pathway from academic demands to academic burnout. The high-stress mindset group demonstrated pathways from academic resources to academic burnout and engagement.
Conclusions: These findings highlight the significance of a stress mindset in enhancing the academic mental health of high school students. KCI Citation Count: 0
The mesenchymal stem cells (MSCs), which are derived from the mesoderm, are considered as a readily available source for tissue engineering. They have multipotent differentiation capacity and can be ...differentiated into various cell types. Many studies have demonstrated that the MSCs identified from amniotic membrane (AM-MSCs) and amniotic fluid (AF-MSCs) are shows advantages for many reasons, including the possibility of noninvasive isolation, multipotency, self-renewal, low immunogenicity, anti-inflammatory and nontumorigenicity properties, and minimal ethical problem. The AF-MSCs and AM-MSCs may be appropriate sources of mesenchymal stem cells for regenerative medicine, as an alternative to embryonic stem cells (ESCs). Recently, regenerative treatments such as tissue engineering and cell transplantation have shown potential in clinical applications for degenerative diseases. Therefore, amnion and MSCs derived from amnion can be applied to cell therapy in neuro-degeneration diseases. In this review, we will describe the potential of AM-MSCs and AF-MSCs, with particular focus on cures for neuronal degenerative diseases.
Purpose: This study aimed to evaluate the utility of acanthosis nigricans (AN) severity as an index for predicting insulin resistance in obese children.Methods: The subjects comprised 74 obese ...pediatric patients who attended the Department of Pediatrics at Chosun University Hospital between January 2013 and March 2016. Waist circumference; body mass index; blood pressure; fasting glucose and fasting insulin levels; lipid profile; aspartate transaminase, alanine transaminase, glycated hemo-globin, C-peptide, and uric acid levels; and homeostatic model assessment insulin resistance (HOMA-IR) and quanti-tative insulin check sensitivity index (QUICKI) scores were compared between subjects with AN and those without AN. Receiver operating characteristic curves were used to investigate the utility of the AN score in predicting insulin resistance. HOMA-IR and QUICKI were compared according to AN severity.Results: The With AN group had higher fasting insulin levels (24.1±21.0 mU/L vs. 9.8±3.6 mU/L, p<0.001) and HOMA-IR score (5.74±4.71 vs. 2.14±0.86, p<0.001) than the Without AN group. The AN score used to predict insulin resistance was 3 points or more (sensitivity 56.8%, specificity 83.9%). HOMA-IR scores increased with AN severity, from the Without AN group (mean, 2.15; 95% confidence interval CI, 1.72-2.57) to the Mild AN (mean, 4.15; 95% CI, 3.04-5.25) and Severe AN groups (mean, 7.22; 95% CI, 5.08-9.35; p<0.001).Conclusion: Insulin resistance worsens with increasing AN severity, and patients with Severe AN (AN score ≥3) are at increased risk of insulin resistance. KCI Citation Count: 0
병원 간호사의 간호조직문화와 간호근무환경이 조직 내 세대갈등에 미치는 영향 권지은(Kwon, Jieun); 김은영(Kim, Eun-Young)
Kanho Haengjŏng Hakhoe chi = The journal of Korean Nursing Administration Academic Society,
2023, Volume:
29, Issue:
1
Journal Article
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