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  • Hypertension contributes to... Hypertension contributes to exacerbated osteoarthritis pathophysiology in rats in a sex-dependent manner
    Yeater, Taylor D; Griffith, Jacob L; Cruz, Carlos J ... Arthritis research & therapy, 01/2023, Volume: 25, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Hypertension is a common comorbidity of osteoarthritis (OA) with known autonomic dysregulation; thus, the autonomic nervous system may provide a shared underlying mechanism. The objective of this ...
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  • Human dermal microvascular ... Human dermal microvascular endothelial cell morphological response to fluid shear stress
    Polk, Tabatha; Schmitt, Sarah; Aldrich, Jessica L. ... Microvascular research, 09/2022, Volume: 143
    Journal Article
    Peer reviewed

    As the cells that line the vasculature, endothelial cells are continually exposed to fluid shear stress by blood flow. Recent studies suggest that the morphological response of endothelial cells to ...
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  • Non-Invasive Electromagneti... Non-Invasive Electromagnetic Skin Patch Sensor to Measure Intracranial Fluid-Volume Shifts
    Griffith, Jacob; Cluff, Kim; Eckerman, Brandon ... Sensors, 03/2018, Volume: 18, Issue: 4
    Journal Article
    Peer reviewed
    Open access

    Elevated intracranial fluid volume can drive intracranial pressure increases, which can potentially result in numerous neurological complications or death. This study's focus was to develop a passive ...
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  • Comprehensive molecular pro... Comprehensive molecular profiling of 718 Multiple Myelomas reveals significant differences in mutation frequencies between African and European descent cases
    Manojlovic, Zarko; Christofferson, Austin; Liang, Winnie S ... PLOS genetics, 11/2017, Volume: 13, Issue: 11
    Journal Article
    Peer reviewed
    Open access

    Multiple Myeloma (MM) is a plasma cell malignancy with significantly greater incidence and mortality rates among African Americans (AA) compared to Caucasians (CA). The overall goal of this study is ...
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  • Enrichment of PI3K-AKT-mTOR... Enrichment of PI3K-AKT-mTOR Pathway Activation in Hepatic Metastases from Breast Cancer
    Pierobon, Mariaelena; Ramos, Corinne; Wong, Shukmei ... Clinical cancer research, 08/2017, Volume: 23, Issue: 16
    Journal Article
    Peer reviewed
    Open access

    Little is known about the molecular signatures associated with specific metastatic sites in breast cancer. Using comprehensive multi-omic molecular profiling, we assessed whether alterations or ...
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  • Somatic inactivating PTPRJ ... Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine malignant melanoma by integrated comparative genomic analysis
    Hendricks, William P D; Zismann, Victoria; Sivaprakasam, Karthigayini ... PLOS genetics, 09/2018, Volume: 14, Issue: 9
    Journal Article
    Peer reviewed
    Open access

    Canine malignant melanoma, a significant cause of mortality in domestic dogs, is a powerful comparative model for human melanoma, but little is known about its genetic etiology. We mapped the genomic ...
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  • In situ fixation and subseq... In situ fixation and subsequent collection of cultured endothelial cells in a shear flow
    Aldrich, Jessica L.; Long, David S. MethodsX, 01/2019, Volume: 6
    Journal Article
    Peer reviewed
    Open access

    Display omitted In situ fixation of adherent cells is a necessary process for downstream assays. Current methods to dissociate adherent endothelial cells require the use of a cell scraper that may ...
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  • Drug Delivery Strategies an... Drug Delivery Strategies and Nanozyme Technologies to Overcome Limitations for Targeting Oxidative Stress in Osteoarthritis
    Aldrich, Jessica Lee; Panicker, Arjun; Ovalle, Jr, Robert ... Pharmaceuticals, 07/2023, Volume: 16, Issue: 7
    Journal Article
    Peer reviewed
    Open access

    Oxidative stress is an important, but elusive, therapeutic target for osteoarthritis (OA). Antioxidant strategies that target oxidative stress through the elimination of reactive oxygen species (ROS) ...
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  • Multi‐omic molecular profil... Multi‐omic molecular profiling guide’s efficacious treatment selection in refractory metastatic breast cancer: a prospective phase II clinical trial
    Pierobon, Mariaelena; Robert, Nicholas J.; Northfelt, Donald W. ... Molecular oncology, January 2022, Volume: 16, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    This prospective phase II clinical trial (Side Out 2) explored the clinical benefits of treatment selection informed by multi‐omic molecular profiling (MoMP) in refractory metastatic breast cancers ...
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Available for: FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SAZU, SBCE, SBMB, UL, UM, UPUK

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