The Muhammadiyah Dlanggu Orphanage Mojokerto is a place to educate children who are disadvantaged in teaching from their parents, because of problems from 40 children, some who disobey, who like to ...disobey the rules, the Muhammadiyah Orphanage Mojokerto has programs for character briefing child. This study aims to determine the implications of the cultivation of moral values to foster children. The research design used is qualitative, with data collection methods namely observation, interviews, and documentation. Data analysis techniques with Flow Model which includes data reduction, data display, conclusion. The conclusions of this study are: the process of planting the character values of an orphanage by instilling the value of akhlakhul karimah through a religious approach, cultural values, environment, self potential, and daily life. The implication is that foster children get new knowledge learning that can change their daily lives for the better. The inhibiting factor is that the origin of the environment is not good because of the number of naughty children and lack of cultivation of moral values since childhood from their parents.
The isolates of Staphylococcus aureus were isolated from patients with various infections in hospitals, the isolates were identified and accurately diagnosed by phenotypic examination and biochemical ...tests, as well Vitek-2, and then genetic detection and diagnosis of many of the pathogenic factors associated with Staphylococcus aureus using conventional polymerase chain reaction (PCR) and testing for association by antibiotic resistance and production of some toxins by Staphylococcus aureus. After performing analysis of statistical, it was set up that the correlation coefficient of the PCR technique using virulence genes, sensitivity test to antibiotics and other virulence factors were significant at p < 0.05, but was insignificant with the biofilm production.
A colorimetric portable setup was developed for remote UA measurements using a smartphone-based application to demonstrate its use in point-of-care testing. Quantitative and affordable point-of-care ...health diagnostics is a rapidly evolving field using nanostructured materials for the detection of various disease biomarkers. The detection of uric acid is of great importance to identify many health syndromes and to avoid relevant complications. Herein, a selective, sensitive, and quantitative detection of uric acid on a cellulose fiber strip using citrate-capped platinum nanoparticles (PtNPs) as a nanozyme is reported for the first time. A reduction method was followed to synthesize the PtNPs (8-10 nm), which were characterized using UV-vis spectroscopy, XRD, and TEM to determine their properties. Morphological characterization of the cellulose substrate was performed using FESEM. A strip was developed having a circular shaped head of 8 mm diameter, which was pretreated with PVA, TMB + H
2
O
2
, and PtNPs, respectively. In the presence of PtNPs (enzyme catalytic activity), TMB acted as a hydrogen donor to reduce H
2
O
2
, giving a bluish-green color on the substrate. The developed method provided a wide linear response from 0 mM to 8 mM for uric acid samples, with the results indicating the downregulating activity of the PtNPs. A calculated LOD of 4.2 ± 5 μM was achieved and the results showed a linear response till 7 mM in terms of the color observation. In conclusion, the developed sensing system could be potentially applicable for the quantitative detection of uric acid in the physiological range in urine samples.
A colorimetric portable setup was developed for remote UA measurements using a smartphone-based application to demonstrate its use in point-of-care testing.
This paper reports a fast, linear, all-range sensitive and biocompatible humidity sensor using poly lactic glycolic acid (PLGA) as a sensing layer for the first time. The device is fabricated using ...all printing methods. The high definition interdigitated electrode structure was printed on flexible PET substrate by reverse offset printing setup using silver ink, while PLGA ink was deposited using spin coating. IDEs with two different dimensions were printed with three samples of each. The output of sensor is impedance which decreases with increase in relative humidity in a controlled chamber. The results show excellent stability, obvious response to RH for full range from 0 to 100 %RH with fast response time of 3 s and recovery time of 6 s. Sensor data can be received continuously using smart phone with a Wi-Fi connection with ESP8266 MCUNODE. Sensor’s flexibility test was also performed for 5 mm mechanical bending radius which showed reasonable consistency with results of flat sensor. The biocompatibility of sensor’s active layer was analyzed and confirmed by culturing human small air way epithelial cells for 7 days. To utilize sensor’s feature of being biocompatible, it was then used for human respiration monitoring which enabled the proposed device to be strong candidate for wearable electronics and health monitoring applications.
Full text
Available for:
EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, KILJ, KISLJ, MFDPS, NLZOH, NUK, OBVAL, OILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ
Inflammatory bowel disease (IBD) is a persistent, lifelong inflammation of the digestive system. Dextran sulfate sodium is commonly used to induce colitis in experimental animal models, which causes ...epithelial damage, intestinal inflammation, mucin depletion, and dysbiosis of the gut microbiota. Various prebiotics, polysaccharides, and polypeptides are used for IBD treatment. In this study, we used a murine model utilizing BALB/c mice, with 10 mice per group, to investigate the treatment effect of sea conch peptide hydrolysate (CPH) on DSS-induced colitis mice. Colitis was induced through the administration of 2.5% DSS in drinking water over a seven-days period. Furthermore, on the eighth day of the experiment, sea conch peptide hydrolysate (CPH) at low (100 mg/kg), medium (200 mg/kg), and high (400 mg/kg) doses, which were continued for 14 days, were assessed for medicinal purposes in DSS-induced colitis mice. Our results showed that CPH treatment significantly alleviated the severity and symptoms of colitis. The epithelial integrity and histological damage were improved. Intestinal inflammation and inflammatory cell infiltration were improved. Furthermore, the expression of pro-inflammatory cytokines was reduced, and intestinal barrier integrity was restored by elevating the tight junction proteins. Moreover, 16s RNA sequencing revealed dysbiosis of the gut microbiota was observed upon DSS treatment, which was reinstated after CPH treatment. An increased level of Firmicutes and Lactobacillus was observed in the treatment groups. Finally, our results suggest that CPH would be recommended as a functional food source and also have the potential to be used as a medicinal product for different gastrointestinal disorders.
Full text
Available for:
IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK
Horizontal-axis wind turbines are the most popular wind machines in operation today. These turbines employ aerodynamic blades that may be oriented either upward or downward. HAWTs are the most common ...non-conventional source of energy generation. These turbine blades fail mostly due to fatigue, as a large centrifugal force acts on them at high rotational speeds. This study aims to increase a turbine's service life by improving the turbine blades' fatigue life. Predicting the fatigue life and the design of the turbine blade considers the maximum wind speed range. SolidWorks, a CAD program, is used to create a wind turbine blade utilizing NACA profile S814. The wind turbine blade's fatigue life is calculated using Morrow's equation. A turbine blade will eventually wear out due to several forces operating on it. Ansys software is used to analyze these stresses using the finite element method. The fatigue study of wind turbine blades is described in this research paper. To increase a turbine blade's fatigue life, this research study focuses on design optimization. Based on the foregoing characteristics, an improved turbine blade design with a longer fatigue life than the original one is intended in this study. The primary fatigue parameters are the length of a chord twist angle and blade length. The experimental data computed with the aid of a fatigue testing machine are also used to validate the numerical results, and it is found that they are very similar to one another. By creating the most effective turbine blades with the longest fatigue life, this research study can be developed further. The most effective turbine blades with the longest fatigue life can be designed to further this research investigation.
Full text
Available for:
IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK
Display omitted
•Deglet Noor Polysaccharides: Investigates their potential in mitigating antibiotic-induced gut dysbiosis.•Restorative Effects: Reverses dysbiosis by enriching beneficial bacteria and ...suppressing pathogens.•Enhanced Mucin Production: Improves gut barrier integrity.•Anti-inflammatory Response: Suppresses cytokines, suggesting therapeutic potential for gut disorders.
Despite their well-known nutritional importance, the consumption of dates is linked to several health benefits. This study investigates the potential of Deglet Noor polysaccharides (DP) in reverting gut dysbiosis. The study aimed to characterize and explore the prebiotic properties of Deglet Noor date polysaccharides (DP) in alleviating antibiotic-induced diarrhea by enhancing intestinal integrity, increasing mucin production, and modulating gut microbiota. Male BALB/C 5–6-week-old mice were utilized, with amoxicillin administered for 14 days followed by treatment with DP for the subsequent 14 days. The alteration of intestinal flora due to antibiotics and the restorative effects of DP were explored using the “Illumina MiSeq platform”. Amoxicillin administration for 14 days resulted in a significant reduction in the diversity and abundance of bacteria, altering the intestinal flora at various taxonomic levels. Antibiotic treatment led to an increase in pathogenic strains (Proteobacteria, Enterococcus, and Bacteroides), while supplementation with DP reversed the antibiotic-induced dysbiosis and increased the richness of beneficial bacteria such as Lachnospiraceae_NK4A136 and Ruminococcaceae within Firmicutes. As a main component of chemical barrier, Mucin-2 expression was depleted with antibiotic treatment, whereas DP demonstrated a healing effect by increasing mucin production. Additionally, DP exhibited an anti-inflammatory response by suppressing the production of inflammatory cytokines including IL-6, IL-17, and TNF-α, while also increasing the expression of tight junction proteins. These results offer important insights into how Deglet Noor polysaccharides can act as prebiotics and improve gut health. They highlight the importance of these polysaccharides in improving the gut barrier and reducing inflammation.
Full text
Available for:
GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP
Abstract
The effect of adding pomegranate peel extract to Grape seed oil and studying the effect of addition on the stability of oil during storage period and comparing the results with a sample of ...grape seed oil during the storage period fortified with the same percentage of BHA. It was found that the addition process improved the physicochemical properties of oil, as it was noted that the value of peroxide number of oil which treated with pomegranate extract amounted to 34.07 μg / g, while the value of the same characteristic for the oil treated with BHA was 28.02 μg / g It was found from study of the rest of traits that their value was less than that of the untreated grape seed oil, and it was found that the absorption of light was less in the treated oil than in the untreated oil. total phenols. And the rest of the characteristics, but it is not having ability of BHA, which works to maintain levels of physicochemical properties within acceptable limits almost.
Elimination of urogenital schistosomiasis transmission is a priority for the Zanzibar Ministry of Health. Preventative chemotherapy together with additional control interventions have successfully ...alleviated much of the disease burden. However, a persistently high Schistosoma haematobium prevalence is found in certain areas. Our aim was to characterise and evaluate these persistent "hot-spots" of transmission and reinfection in comparison with low-prevalence areas, to support the intervention planning for schistosomiasis elimination in Zanzibar.
Prevalences of S. haematobium were annually determined by a single urine filtration in schoolchildren from 45 administrative areas (shehias) in Unguja in 2012, 2013 and 2014. Coverage data for biannual treatment with praziquantel were available from ministerial databases and internal surveys. Among the 45 shehias, five hot-spot (≥ 15 % prevalence) and two low-prevalence (≤ 5 %) shehias were identified and surveyed in mid-2014. Human-water contact sites (HWCSs) and the presence of S. haematobium-infected and uninfected Bulinus globosus, as well as safe water sources (SWSs) and their reliability in terms of water availability were determined and mapped.
We found no major difference in the treatment coverage between persistent hot-spot and low-prevalence shehias. On average, there were considerably more HWCSs containing B. globosus in hot-spot than in low-prevalence shehias (n = 8 vs n = 2) and also more HWCSs containing infected B. globosus (n = 2 vs n = 0). There was no striking difference in the average abundance of SWSs in hot-spot and low-prevalence shehias (n = 45 vs n = 38) and also no difference when considering SWSs with a constant water supply (average: 62 % vs 62 %). The average number of taps with a constant water supply, however, was lower in hot-spot shehias (n = 7 vs n = 14). Average distances from schools to the nearest HWCS were considerably shorter in hot-spot shehias (n = 229 m vs n = 722 m).
The number of HWCSs, their infestation with B. globosus and their distance to schools seem to play a major role for a persistently high S. haematobium prevalence in children. In addition to treatment, increasing access to reliably working taps, targeted snail control at HWCSs near schools and enhanced behaviour change measures are needed to reduce prevalences in hot-spot areas and to finally reach elimination.
ISRCTN48837681 .
Full text
Available for:
IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK
PDF
